Technology Process of C23H19N5O2
There total 9 articles about C23H19N5O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: sulfuric acid; nitric acid / 0.5 h / -10 - -5 °C
2: sulfuric acid / 1.58 h / 47 - 56 °C
3: hydrogenchloride; sodium nitrite / water / 0.5 h / 0 °C
4: potassium carbonate / tetrahydrofuran / 0 - 50 °C
5: bis-triphenylphosphine-palladium(II) chloride / toluene / 2 h / 130 °C / Microwave irradiation; Inert atmosphere
6: hydrogen / tetrahydrofuran; methanol / 1 h / 20 °C / 4137.29 Torr
7: tetrahydrofuran / 18 h / 20 °C
With
hydrogenchloride; bis-triphenylphosphine-palladium(II) chloride; sulfuric acid; hydrogen; nitric acid; potassium carbonate; sodium nitrite;
In
tetrahydrofuran; methanol; water; toluene;
5: Stille coupling;
DOI:10.1016/j.tetlet.2011.08.119
- Guidance literature:
-
Multi-step reaction with 9 steps
1: sulfuric acid; nitric acid / 3.92 h / 79 - 85 °C
2: iron; acetic acid / 0.75 h
3: sulfuric acid; nitric acid / 0.5 h / -10 - -5 °C
4: sulfuric acid / 1.58 h / 47 - 56 °C
5: hydrogenchloride; sodium nitrite / water / 0.5 h / 0 °C
6: potassium carbonate / tetrahydrofuran / 0 - 50 °C
7: bis-triphenylphosphine-palladium(II) chloride / toluene / 2 h / 130 °C / Microwave irradiation; Inert atmosphere
8: hydrogen / tetrahydrofuran; methanol / 1 h / 20 °C / 4137.29 Torr
9: tetrahydrofuran / 18 h / 20 °C
With
hydrogenchloride; bis-triphenylphosphine-palladium(II) chloride; sulfuric acid; hydrogen; nitric acid; iron; potassium carbonate; acetic acid; sodium nitrite;
In
tetrahydrofuran; methanol; water; toluene;
7: Stille coupling;
DOI:10.1016/j.tetlet.2011.08.119