39771-34-1

Usage

Uses

Used in Pharmaceutical Industry:
4-Amino-2,6-dibromopyridine is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to form diverse chemical structures and functional groups, contributing to the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
4-Amino-2,6-dibromopyridine is used as a building block in the production of agrochemicals, such as pesticides and herbicides, due to its reactivity and potential to create effective and targeted active ingredients.
Used in Dye and Pigment Industry:
4-Amino-2,6-dibromopyridine is used as a precursor in the manufacturing of dyes and pigments, enabling the creation of a wide range of colors and shades for various applications, including textiles, plastics, and printing inks.
Used in Organic Synthesis:
4-Amino-2,6-dibromopyridine is utilized as a versatile reagent in organic synthesis, allowing the formation of various functional groups and complex molecular structures, which can be further used in the development of new compounds and materials.
Due to its high reactivity and potential hazards, 4-Amino-2,6-dibromopyridine is handled with caution in laboratories and industrial settings, ensuring proper safety measures are in place to minimize risks.

InChI:InChI=1/C5H4Br2N2/c6-4-1-3(8)2-5(7)9-4/h1-2H,(H2,8,9)

Upstream product

• 2408-70-0 2,4,6-tribromopyridine 
• 7664-41-7 ammonia 
• 71-36-3 butan-1-ol 
• 175422-04-5 2,6-dibromo-4-nitropyridine 

Downstream Products

• 26943-06-6 4-Amino-2,3,5,6-tetrabromopyridin 
• 337917-94-9 2,6-dibromo-4-phenylpyridine 
• 202467-46-7 N-[4-(2,6-dibromopyridin-4-ylsulfamoyl)phenyl]acetamide 
• 202467-14-9 4-amino-N-(2,6-dibromopyridin-4-yl)benzenesulfonamide 
• 202466-76-0 4-amino-N-(2-bromo-6-methylaminopyridin-4-yl)benzenesulfonamide 
• 848470-14-4 2,6-dibromo-3-nitropyridin-4-ylamine 
• 1160787-08-5 N-(2,6-dibromopyridin-4-ylcarbamothioyl)benzamide 
• 1303438-96-1 N-benzyl-2,6-dibromo-3-nitropyridin-4-amine 
• 1303438-97-2 N₄-benzyl-2,6-dibromopyridine-3,4-diamine 
• 1303438-98-3 1-benzyl-5,7-dibromopyrido[4,3-b]pyrazine-2,3(1H,4H)-dione 
• 1303438-99-4 5-amino-1-benzyl-7-bromopyrido[4,3-b]pyrazine-2(1H,4H)-dione 
• 1303439-12-4 tert-butyl benzyl(2,6-dibromo-3-nitropyridin-4-yl)carbamate 
• 1428798-11-1 C₂₅H₂₂N₂O₂ 
• 947145-72-4 (3-cyano-benzyl)-(2,6-dibromo-3-nitro-pyridin-4-yl)-carbamic acid ethyl ester 

Relevant academic research and scientific papers

ANTIBACTERIAL COMPOSITIONS

Compounds of formula (I) have antibacterial activity wherein: m is O or 1; Q is hydrogen or cyclopropyl; AIk is an optionally substituted, divalent C1-C3 alkylene, C2-C3 alkenylene or C2-C3 alkynylene radical; X is - C(=O)NH- or -C(=O)O-; R2 and R3 are as defined in the specification.

PHARMACOLOGICALLY ACTIVE IMIDAZO[4,5-C]PYRIDINES

The invention relates to 6-substituted imidazo[4,5-c]pyridines of formula 1, in which X is O (oxygen) or NH and Y has either the meaning -CH2-AR or Y denotes the group gp (gp) wherein Z has the meaning -CHR8- or -CHR8-CHR9-. The compounds have gastric secretion inhibiting and excellent gastric and intestinal protective action properties.

The development of a practical and reliable large-scale synthesis of 2,6-diamino-4-bromopyridine

A novel, safer, and efficient synthetic route to 2,6-diamino-4-bromopyridine has been developed. In discovery research a five-step synthesis afforded 2,6-diamino-4-bromopyridine in 56% yield with a double Curtius rearrangement as a key transformation. Due to potential safety concerns on larger scale an alternative synthetic strategy was necessary. Starting from 2,4-dibromopyridine-N-oxide two complementary procedures have been developed to access 2,6-diamino-4-bromopyridine. The four-step procedure yielded in 28% overall, and the five-step procedure, in 33% overall 2,6-diamino-4-bromopyridine in a safe and straightforward manner using a regioselective 2,6-diamination reaction as key step. Additionally, a general route to unsymmetrical substituted pyridine N-oxide derivatives is disclosed.