N-phenyl-1-(2-vinylphenyl)methanimine

Base Information

• Chemical Name: N-phenyl-1-(2-vinylphenyl)methanimine
• CAS No.: 852546-91-9
• Molecular Formula: C₁₅H₁₃N
• Molecular Weight: 207.275
• Mol file: 852546-91-9.mol

Synonyms:N-phenyl-1-(2-vinylphenyl)methanimine

Chemical Property of N-phenyl-1-(2-vinylphenyl)methanimine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of N-phenyl-1-(2-vinylphenyl)methanimine

There total 2 articles about N-phenyl-1-(2-vinylphenyl)methanimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-vinylbenzaldehyde (28272-96-0) + aniline (62-53-3) → N-phenyl-1-(2-vinylphenyl)methanimine (852546-91-9)

Guidance literature:

With magnesium sulfate; In dichloromethane; at 23 ℃; for 24h; Inert atmosphere;

DOI:10.1021/acs.orglett.9b04233

Reference yield:

2-bromostyrene (2039-88-5) → N-phenyl-1-(2-vinylphenyl)methanimine (852546-91-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: iodine; magnesium / tetrahydrofuran / 5 h / Inert atmosphere; Reflux

1.2: 12 h / 45 °C / Inert atmosphere

2.1: magnesium sulfate / dichloromethane / 24 h / 23 °C / Inert atmosphere

With iodine; magnesium sulfate; magnesium; In tetrahydrofuran; dichloromethane;

DOI:10.1021/acs.orglett.9b04233

Reference yield: 83.0%

N-phenyl-1-(2-vinylphenyl)methanimine (852546-91-9) + (2-(1,3-dioxan-2-yl)ethyl)zinc(II) bromide + benzyl bromide (100-39-0) → 4-phenethyl-3,4-dihydronaphthalene-2-carbaldehyde

Guidance literature:

N-phenyl-1-(2-vinylphenyl)methanimine; (2-(1,3-dioxan-2-yl)ethyl)zinc(II) bromide; benzyl bromide; With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; at 20 ℃; for 6h; Inert atmosphere; Sealed tube;

With hydrogenchloride; water; In tetrahydrofuran; 1,4-dioxane; at 20 ℃; for 6h; regioselective reaction; Inert atmosphere;

DOI:10.1021/jacs.0c09778 DOI:10.1021/jacs.1c06574

upstream raw materials:

2-vinylbenzaldehyde

aniline

2-bromostyrene