T338C Src-IN-2

Base Information

Chemical Name:T338C Src-IN-2
CAS No.:1351927-00-8
Molecular Formula:C₁₇H₁₈FN₅O
Molecular Weight:327.361
Hs Code.:
Mol file:1351927-00-8.mol

Synonyms:1-(3-((4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl)phenyl)-2-fluoroethanone

Suppliers and Price of T338C Src-IN-2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
T338CSrc-IN-2 >98%
10 mg
$ 400.00

DC Chemicals
T338CSrc-IN-2 >98%
50 mg
$ 1200.00

Biorbyt Ltd
T338C Src-IN-2
100 mg
$ 2512.60

Biorbyt Ltd
T338C Src-IN-2
50 mg
$ 1802.00

Biorbyt Ltd
T338C Src-IN-2
10 mg
$ 615.40

Total 7 raw suppliers

Chemical Property of T338C Src-IN-2

Chemical Property:

Boiling Point:540.6±50.0 °C(Predicted)
PKA:4.31±0.30(Predicted)
Density:1.35±0.1 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

T338CSrc-IN-2 >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of T338C Src-IN-2

There total 6 articles about T338C Src-IN-2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

: 3-(3-acetylbenzyl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-di-t-butoxycarbonyl amine

: 1351927-00-8
1-(3-((4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl)phenyl)-2-fluoroethanone

Guidance literature:: 3-(3-acetylbenzyl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-di-t-butoxycarbonyl amine; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.25h;

With N-fluorobis(benzenesulfon)imide; In tetrahydrofuran; at 20 ℃; for 0.5h;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 5h;

Reference yield:

: 1878-67-7
3-Bromophenylacetic acid

: 1351927-00-8
1-(3-((4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl)phenyl)-2-fluoroethanone

Guidance literature:: Multi-step reaction with 6 steps

1.1: oxalyl dichloride / dichloromethane / 0.5 h / 20 °C

1.2: 2 h / 0 - 20 °C

1.3: 16 h / 20 - 70 °C

2.1: triethylamine / ethanol / 1 h / 20 °C

3.1: 27 h / 160 °C

4.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 16 h / 120 °C

4.2: 12 h / 20 °C

5.1: dmap / 3 h / 20 °C

6.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.25 h / -78 °C

6.2: 0.5 h / 20 °C

6.3: 5 h / 20 °C

With dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; oxalyl dichloride; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; ethanol; dichloromethane; toluene;

Reference yield:

: 1351926-98-1
3-(3-acetylbenzyl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

: 1351927-00-8
1-(3-((4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl)phenyl)-2-fluoroethanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: dmap / 3 h / 20 °C

2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.25 h / -78 °C

2.2: 0.5 h / 20 °C

2.3: 5 h / 20 °C

With dmap; lithium hexamethyldisilazane; In tetrahydrofuran;