1351926-98-1

Basic information

• Product Name: 3-(3-acetylbenzyl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• Synonyms: 3-(3-acetylbenzyl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• CAS NO: 1351926-98-1
• Molecular Weight: 309.371
• Mol File: 1351926-98-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3-acetylbenzyl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-acetylbenzyl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine(1351926-98-1)
• EPA Substance Registry System: 3-(3-acetylbenzyl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine(1351926-98-1)

Safety Data

• Hazardous Substances Data: 1351926-98-1(Hazardous Substances Data)

Upstream product

• 1351926-97-0 3-(3-bromobenzyl)-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 97674-02-7 tributyl(1-ethoxyvinyl)stannane 
• 1351926-96-9 5-amino-3-(3-bromobenzyl)-1-isopropyl-1H-pyrazole-4-carbonitrile 
• 1878-67-7 3-Bromophenylacetic acid 
• 1364226-31-2 2-(methoxy-(3-bromobenzyl)methylene)malononitrile 

Downstream Products

• 1351927-00-8 1-(3-((4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl)phenyl)-2-fluoroethanone 

Relevant articles and documents

METHODS AND COMPOSITIONS FOR KINASE INHIBITION

The present invention sets forth a new chemical genetic approach for engineering kinase enzymes with a cysteine gatekeeper residue as well as for developing electrophilic inhibitors thereto. The present invention also provides a Src proto-oncogenic tyrosine kinase with a cysteine gatekeeper that recapitulates wild type activity and can be irreversibly inhibited both in vitro and in cells. The present invention also provides methods and compositions for modulating kinases and for treating kinase-associated diseases.