N-Methyl-N-nitroso-p-nitrobenzylamine

Base Information

• Chemical Name: N-Methyl-N-nitroso-p-nitrobenzylamine
• CAS No.: 84174-24-3
• Molecular Formula: C₈H₉N₃O₃
• Molecular Weight: 195.178
• Hs Code.: 2928000090
• Mol file: 84174-24-3.mol

Synonyms:BENZYLAMINE,N-METHYL-p-NITRO-N-NITROSO;N-Methyl-p-nitro-N-nitrosobenzylamine;N-Nitrosomethyl-4-nitrobenzylamine;

Chemical Property of N-Methyl-N-nitroso-p-nitrobenzylamine

Chemical Property:

• Vapor Pressure: 1.47E-06mmHg at 25°C
• Boiling Point: 410.1°C at 760 mmHg
• Flash Point: 201.8°C
• PSA: 78.49000
• Density: 1.29g/cm³
• LogP: 2.23120

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Methyl-N-nitroso-p-nitrobenzylamine

There total 3 articles about N-Methyl-N-nitroso-p-nitrobenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-methyl-4-nitrobenzylamine (19499-60-6) → N-nitroso-N-(p-nitrobenzyl)methylamine (84174-24-3)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water; acetic acid; Ambient temperature;

DOI:10.1021/jm00151a006

Reference yield:

1-bromomethyl-4-nitro-benzene (100-11-8) → N-nitroso-N-(p-nitrobenzyl)methylamine (84174-24-3)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 6 h / Heating

2: NaNO₂, aq. HCl / acetic acid; H₂O / Ambient temperature

With hydrogenchloride; sodium nitrite; In ethanol; water; acetic acid;

DOI:10.1021/jm00151a006

Reference yield:

methylamine (74-89-5) + 1-bromomethyl-4-nitro-benzene (100-11-8) → N,N-bis(p-nitrobenzyl)methylamine (32578-23-7) + N-nitroso-N-(p-nitrobenzyl)methylamine (84174-24-3)

Guidance literature:

In methanol; for 65h; Yield given. Yields of byproduct given; Heating;

DOI:10.1021/jm00357a001

upstream raw materials:

N-methyl-4-nitrobenzylamine

methylamine

1-bromomethyl-4-nitro-benzene

Refernces

• 1、 Singer, George M.,Andrews, A.W.. "Mutagenicity and Chemistry of N-Nitroso-N-(p-substituted-benzyl)methylamines". . p. 309 - 312. Retrieved 2007/10/02.