α-Cyano-2-thienyl Benzoate

Base Information

• Chemical Name: α-Cyano-2-thienyl Benzoate
• CAS No.: 129803-27-6
• Molecular Formula: C₁₃H₉NO₂S
• Molecular Weight: 243.286
• Mol file: 129803-27-6.mol

Synonyms:α-Cyano-2-thienyl Benzoate

Chemical Property of α-Cyano-2-thienyl Benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of α-Cyano-2-thienyl Benzoate

There total 4 articles about α-Cyano-2-thienyl Benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

thiophene-2-carbaldehyde (98-03-3) + benzoyl cyanide (613-90-1) → α-Cyano-2-thienyl Benzoate (129803-27-6)

Guidance literature:

With triethylamine; In acetonitrile; at 20 ℃;

DOI:10.1021/acs.orglett.1c01762

Reference yield:

thiophene-2-carbonyl cyanide (6007-78-9) + benzaldehyde (100-52-7) → α-Cyano-2-thienyl Benzoate (129803-27-6)

Guidance literature:

With triethylamine; In acetonitrile; at 20 ℃;

DOI:10.1002/adsc.202000125

Reference yield:

benzoyl fluoride (455-32-3) + 2-(thiophen-2-yl)-2-((trimethylsilyl)oxy)acetonitrile (139224-74-1,82069-26-9) → α-Cyano-2-thienyl Benzoate (129803-27-6)

Guidance literature:

With dmap; In acetonitrile; at 20 ℃; for 12h;

DOI:10.1055/s-2007-968028

upstream raw materials:

thiophene-2-carbaldehyde

benzoyl cyanide

benzoyl fluoride

2-(thiophen-2-yl)-2-((trimethylsilyl)oxy)acetonitrile