Dabigatran Impurity 8

Base Information

Chemical Name:Dabigatran Impurity 8
CAS No.:1408238-40-3
Molecular Formula:C₃₄H₄₀N₆O₆
Molecular Weight:628.728
Hs Code.:
Mol file:1408238-40-3.mol

Synonyms:ethyl 3-[[[2-[[[4-[[[(hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propanoate

Suppliers and Price of Dabigatran Impurity 8

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanineEthylEster
50mg
$ 105.00

TRC
N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanineEthylEster
1g
$ 1555.00

TRC
N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanineEthylEster
250mg
$ 470.00

Crysdot
Ethyl3-(2-(((4-(((hexyloxy)carbonyl)carbamoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate 97%
100mg
$ 396.00

Total 17 raw suppliers

Chemical Property of Dabigatran Impurity 8

Chemical Property:

Melting Point:>182°C (dec.)
PKA:10.83±0.46(Predicted)
Density:1.24±0.1 g/cm3(Predicted)
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanineEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine ethyl ester can be used as reference standards and markers. It can also be employed to analyze dabigatran eterxilate,?dabigatran eterxilate mesylate,?and its degraded products by various HPLC methods.

Technology Process of Dabigatran Impurity 8

There total 14 articles about Dabigatran Impurity 8 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1307233-94-8
N-[[2-(chloromethyl)-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridyl-β-alanine ethyl ester

: 4-[[[(hexyloxy)carbonyl]amino]carbonyl]aniline

: 1408238-40-3
ethyl 3-[[[2-[[[4-[[[(hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propanoate

Guidance literature:: With tetra-(n-butyl)ammonium iodide; sodium hydrogencarbonate; sodium iodide; In hexane; water; at 40 - 70 ℃; for 4h;

Reference yield: 81.0%

: 211915-06-9
dabigatran etexilate

: 1408238-40-3
ethyl 3-[[[2-[[[4-[[[(hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propanoate

Guidance literature:: With water; tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; at 20 ℃;

Reference yield: 74.62%

: 123-86-4
acetic acid butyl ester

: C₁₄H₂₀N₂O₃*ClH

: 212322-56-0
ethyl 3-{[{2-amino-1-(methylamino)phen-4-yl}carbonyl](pyridyn-2-yl)amino}propanoate

: 1408238-40-3
ethyl 3-[[[2-[[[4-[[[(hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl](pyridin-2-yl)amino]propanoate

Guidance literature:: With tetrabutyl ammonium fluoride; sodium hydrogencarbonate; sodium iodide; In cyclohexane; water; at 40 ℃; for 2h; Reagent/catalyst;