ASCORBYL GLUCOSIDE

Base Information

• Chemical Name: ASCORBYL GLUCOSIDE
• CAS No.: 129499-78-1
• Molecular Formula: C12H18O11
• Molecular Weight: 338.268
• Hs Code.: 2936270090
• Mol file: 129499-78-1.mol

Synonyms:2-O-α-D-Glucopyranosyl-L-ascorbic acid;AA2G;Ascofresh;Ascorbyl glucoside;L-Ascorbic acid 2-glucoside;L-Ascorbic acid glucoside;

Chemical Property of ASCORBYL GLUCOSIDE

Chemical Property:

• Vapor Pressure: 8.94E-24mmHg at 25°C
• Melting Point: 158-163℃
• Refractive Index: 1.67
• Boiling Point: 717.451 °C at 760 mmHg
• PKA: 3.38±0.10(Predicted)
• Flash Point: 271.813 °C
• PSA: 186.37000
• Density: 1.835 g/cm³
• LogP: -4.14890
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• Water Solubility.: Soluble in water. (879 g/L) at 25°C.

Purity/Quality:

99.5%, ^*data from raw suppliers

L-Ascorbic Acid 2- ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Ascorbyl glucoside is a natural active substance containing Vitamin C structure, but it is stable. Ascorbyl glucoside can effectively inhibit formation of melanin, dilute the skin color, reduce age spots and freckles pigmentation.Ascorbic Acid 2-Glucoside(AA-2G) was originally developed as a quasi-drug cosmetic product in Japan to lighten the overall tone of the skin and reduce the pigmentation in age spots and freckles. Further research has shown other dramatic benefits and today AA-2G is used all over the world-not only for whitening but also for brightening dull looking skin, reversing the effects of aging, and in sunscreen products for protection.
• Uses: According to the manufacturer, ascorbyl glucoside functions as a time-release version of vitamin C (ascorbic acid), and therefore is more stable than traditional ascorbic acid. It is considered to have skin-lightening and anti-hyperpigmentation properties, thanks to an ability to suppress melanin production. Its skinbrightening capacities are attributed to an apparent ability to reduce pre-existing melanin levels (as in the case of freckles or age spots). Ascorbyl glucoside could also help promote collagen synthesis and help reduce skin inflammation. It is found in antiaging, anti-wrinkle, and sun care products. 2-O-alpha-D-Glucopyranosyl-L-ascorbic acid reduce the free radicals that result from UV irradiation of the skin, and significantly reduce cell damage and photo-aging. It also promotes collagen synthesis. It can function as an antioxidant.

Technology Process of ASCORBYL GLUCOSIDE

There total 8 articles about ASCORBYL GLUCOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

ascorbic acid (50-81-7,98966-42-8) + Sucrose (57-50-1) → 2-O-α-D-glucopyranosyl L-ascorbate (129499-78-1,562043-82-7)

Guidance literature:

With Bifidobacterium longum sucrose phosphorylase; In aq. buffer; at 40 ℃; for 72h; pH=5.2; pH-value; Reagent/catalyst; Temperature; regioselective reaction; Catalytic behavior; Enzymatic reaction;

DOI:10.1002/cbic.201700215

Reference yield: 39.0%

ascorbic acid (50-81-7,98966-42-8) + dextrin → 2-O-α-D-glucopyranosyl L-ascorbate (129499-78-1,562043-82-7)

Guidance literature:

ascorbic acid; dextrin; With Geobacillus stearothermophilus Tc-62 cyclomaltodextrin glucanotransferase; In water; at 55 ℃; for 50h; pH=5.5; Enzymatic reaction;

With glucoamylase GLUCZYM AF₆; In water; for 24h; pH=4.5; Reagent/catalyst; Time; Catalytic behavior; Enzymatic reaction;

Reference yield: 14.0%

sodium ascorbate (134-03-2) → 2-O-α-D-glucopyranosyl L-ascorbate (129499-78-1,562043-82-7)

Guidance literature:

rat intestinal (or rice seed) α-glucosidase, maltose, thiourea, 0.1 M acetate buffer, 3 h, 50 deg C, in the dark;

DOI:10.1248/cpb.38.3020

upstream raw materials:

sodium ascorbate

alpha cyclodextrin

ascorbic acid

β‐cyclodextrin

Refernces

• 1、 Zhang, Zichen,Li, Jianghua,Liu, Long,Sun, Jun,Hua, Zhaozhe,Du, Guocheng,Chen, Jian. "Enzymatic transformation of 2-O-α-d-glucopyranosyl-L-ascorbic acid (AA-2G) by immobilized α-cyclodextrin glucanotransferase from recombinant Escherichia coli". . p. 223 - 229. Retrieved 2011.
• 2、 Gudiminchi, Rama Krishna,Towns, Andrew,Varalwar, Subhash,Nidetzky, Bernd. "Enhanced Synthesis of 2-O-α- d -Glucopyranosyl- l -ascorbic Acid from α-Cyclodextrin by a Highly Disproportionating CGTase". . p. 1606 - 1615. Retrieved 2016.
• 3、 -. "METHOD FOR PRODUCING 2-O- ALPHA-D-GLUCOSYL-L-ASCORBIC ACID ANHYDROUS CRYSTAL-CONTAINING POWDER". Paragraph 0125; 0126; 0127; 0128. . Retrieved 2013/11/05.