(4S,5R)-(E)-1-benzyloxy-5-tert-butyldimethylsilyloxy-4-methyl-2-heptene

Base Information

Chemical Name:(4S,5R)-(E)-1-benzyloxy-5-tert-butyldimethylsilyloxy-4-methyl-2-heptene
CAS No.:141858-86-8
Molecular Formula:C₂₁H₃₆O₂Si
Molecular Weight:348.601
Hs Code.:

Synonyms:(4S,5R)-(E)-1-benzyloxy-5-tert-butyldimethylsilyloxy-4-methyl-2-heptene

Suppliers and Price of (4S,5R)-(E)-1-benzyloxy-5-tert-butyldimethylsilyloxy-4-methyl-2-heptene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (4S,5R)-(E)-1-benzyloxy-5-tert-butyldimethylsilyloxy-4-methyl-2-heptene

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (4S,5R)-(E)-1-benzyloxy-5-tert-butyldimethylsilyloxy-4-methyl-2-heptene

There total 12 articles about (4S,5R)-(E)-1-benzyloxy-5-tert-butyldimethylsilyloxy-4-methyl-2-heptene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 111149-40-7
(3R,4S)-(E)-7-benzyloxy-4-methylhept-5-en-3-ol

: 141858-86-8
(4S,5R)-(E)-1-benzyloxy-5-tert-butyldimethylsilyloxy-4-methyl-2-heptene

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; for 14h; Ambient temperature;
DOI:10.3987/COM-91-S80

Reference yield:

: 123372-87-2
(3S,4S)-(E)-7-benzyloxy-4-methylhept-5-en-1-yn-3-ol

: 141858-86-8
(4S,5R)-(E)-1-benzyloxy-5-tert-butyldimethylsilyloxy-4-methyl-2-heptene

Guidance literature:: Multi-step reaction with 4 steps

1: 66 percent / NaHCO₃, N-bromosuccinimide / 1 h / Ambient temperature

2: 80 percent / H₂ / PtO₂ / hexane / 2.5 h / 760 Torr / Ambient temperature

3: 99 percent / Zn, 35percent HCl / methanol / 10 h / Heating

4: 97 percent / imidazole / dimethylformamide / 14 h / Ambient temperature

With 1H-imidazole; hydrogenchloride; N-Bromosuccinimide; hydrogen; sodium hydrogencarbonate; zinc; platinum(IV) oxide; In methanol; hexane; N,N-dimethyl-formamide;
DOI:10.3987/COM-91-S80

Reference yield:

: 111149-37-2,141901-83-9,141901-87-3,141901-88-4,141901-90-8
(4R,5R)-2-Benzyloxymethyl-3-bromo-5-ethyl-4-methyl-tetrahydro-furan

: 141858-86-8
(4S,5R)-(E)-1-benzyloxy-5-tert-butyldimethylsilyloxy-4-methyl-2-heptene

Guidance literature:: Multi-step reaction with 2 steps

1: Zn, MeOH / HCl

2: imidazole / dimethylformamide

With 1H-imidazole; methanol; zinc; hydrogenchloride; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)99306-7