123372-87-2

Upstream product

• 111149-31-6 (3R,4S)-(E)-7-benzyloxy-4-methyl-1-trimethylsilylhept-5-en-1-yn-3-ol 
• 120448-41-1 (3R,4S)-(E)-7-benzyloxy-4-methylhept-5-en-1-yn-3-ol 
• 111149-29-2 (R)-(Z)-1-benzyloxy-2-(3'-trimethylsilylpropargyloxy)-3-pentene 
• 120448-40-0 (R)-(Z)-1-benzyloxy-2-propargyloxy-3-pentene 
• 110339-29-2 (R)-(Z)-1-Benzyloxy-2-hydroxy-3-pentene 
• 141207-20-7 Benzoic acid (E)-(1S,2S)-5-benzyloxy-1-ethynyl-2-methyl-pent-3-enyl ester 

Downstream Products

• 123372-88-3 (3R,4S)-7-Benzyloxy-4-methyl-heptan-3-ol 
• 111149-36-1 (4R,5S)-2-Benzyloxymethyl-3-bromo-5-ethynyl-4-methyl-tetrahydro-furan 
• 111149-36-1 (2S,3S,4RS,5RS)-5-benzyloxymethyl-4-bromo-2-ethynyl-3-methyltetrahydrofuran 
• 103563-54-8 (3R,4S)-(E)-7-<(benzyloxy)methoxy>-4-methyl-5-hepten-3-ol 
• 111149-40-7 (3R,4S)-(E)-7-benzyloxy-4-methylhept-5-en-3-ol 
• 141858-86-8 (4S,5R)-(E)-1-benzyloxy-5-tert-butyldimethylsilyloxy-4-methyl-2-heptene 
• 141858-95-9 (3R,4S)-(E)-7-benzyloxymethoxy-3-tert-butyldimethylsilyloxy-4-methyl-hept-5-ene 
• 111149-37-2 (2R,3S,4RS,5RS)-5-benzyloxymethyl-4-bromo-2-ethyl-3-methyltetrahydrofuran 
• 141207-24-1 (4S,5R)-1-{3-[(4E,8E)-(2R,7R)-10-Benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-5,7-dimethyl-deca-4,8-dienyl]-oxiranyl}-5-(tert-butyl-dimethyl-silanyloxy)-4-methyl-heptan-1-one 
• 141207-25-2 (13E,17E)-(3R,4S,11R,16R)-19-Benzyloxy-3,11-bis-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-4,14,16-trimethyl-nonadeca-13,17-dien-7-one 
• 141207-22-9 (13E,17E)-(3R,4S,11R,16R)-19-Benzyloxy-3,11-bis-(tert-butyl-dimethyl-silanyloxy)-4,14,16-trimethyl-nonadeca-13,17-dien-8-yn-7-one 
• 141207-23-0 (8Z,13E,17E)-(3R,4S,11S,16R)-19-Benzyloxy-3,11-bis-(tert-butyl-dimethyl-silanyloxy)-4,14,16-trimethyl-nonadeca-8,13,17-trien-7-one 
• 141207-21-8 (13E,17E)-(3R,4S,11R,16R)-19-Benzyloxy-11-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-4,14,16-trimethyl-nonadeca-13,17-dien-8-yn-7-one 
• 141207-29-6 (2R,6R,8R,9S)-2-((2E,6E)-(R)-8-Benzyloxy-3,5-dimethyl-octa-2,6-dienyl)-8-ethyl-9-methyl-1,7-dioxa-spiro[5.5]undecan-4-one 

Relevant academic research and scientific papers

ENANTIOCONTROLLED SYNTHESIS OF THE C9-27 SEGMENT OF MILBEMYCIN K FROM (R)- AND (S)-EPICHLOROHYDRINS

The C9-27 segment (11) of milbemycin K (10) has been synthesized usintwo molar equivalents of (R)-epichlorohydrin -and one molar equivalent of (S)-epichlorohydrin (S)-1-as chiral building blocks.

AN ENANTIOCONTROLLED ROUTE TO PROTOMYCINOLIDE IV AND ITS PRESUMED BIOGENETIC PRECURSORS USING (S)-O-BENZYLGLYCIDOL

Starting with (S)-O-benzylglycidol (9) as only chiral building block, a formal synthesis of protomycinolide IV (1) and the first syntheses of its presumed biogenetic precursors methyl epimycinonate I (2), methyl mycinonate I (3), methyl mycinonate II (4),