(2S)-2-Hydroxybutanedioic acid

Base Information Edit

Chemical Name:(2S)-2-Hydroxybutanedioic acid
CAS No.:97-67-6
Deprecated CAS:124501-05-9,498-37-3,6294-10-6,84781-39-5,6294-10-6,84781-39-5
Molecular Formula:C4H6O5
Molecular Weight:134.089
Hs Code.:29181980
European Community (EC) Number:202-601-5
NSC Number:9232
UNII:J3TZF807X5
DSSTox Substance ID:DTXSID30273987
Nikkaji Number:J74.430A
Wikidata:Q27104150
NCI Thesaurus Code:C84394
Metabolomics Workbench ID:37105
ChEMBL ID:CHEMBL1234046
Mol file:97-67-6.mol

Synonyms:97-67-6;L-Malic acid;L-(-)-Malic acid;(S)-2-hydroxysuccinic acid;(2S)-2-Hydroxybutanedioic acid;(S)-Malic acid;L(-)-Malic acid;Apple acid;(-)-Malic acid;L-Apple acid;(-)-Hydroxysuccinic acid;L-malate;S-(-)-Malic acid;L-Hydroxybutanedioic acid;S-2-Hydroxybutanedioic acid;Butanedioic acid, hydroxy-, (2S)-;Malic acid, L-;L-2-Hydroxybutanedioic acid;(S)-(-)-Hydroxysuccinic acid;CHEBI:30797;(-)-L-Malic acid;(S)-malate;Malic acid L-(-)-form;Hydroxysuccinnic acid (-);L-Hydroxysuccinic acid;UNII-J3TZF807X5;Hydroxybutanedioic acid, (S)-;J3TZF807X5;CHEMBL1234046;NSC9232;2-Hydroxybutanedioic acid, (S)-;NSC 9232;NSC-9232;EINECS 202-601-5;C4H6O5;MFCD00064213;Butanedioic acid, 2-hydroxy-, (2S)-;BUTANEDIOIC ACID, HYDROXY-, (S)-;(S)-Hydroxybutanedioic acid;MALATE ION;(-)-(S)-Malic acid;Hydroxybutanedioic acid, (-)-;malic-acid;laevo-malic acid;2yfa;4elc;4ipi;4ipj;L-Maleic Acid;L- malic acid;L-Hydroxysuccinate;(S)-(-)-2-Hydroxysuccinic acid;(2s)-malic acid;L-Hydroxybutanedioate;nchembio867-comp7;L-(-) malic acid;(-)-Hydroxysuccinate;L-(-)-Apple Acid;S-(-)-Malate;(S)-Hydroxybutanedioate;S-2-Hydroxybutanedioate;(-)-(S)-Malate;(S)-(-)-malic acid;(S)-hydroxy-Butanedioate;(S)-Hydroxysuccinic acid;L(-)MALIC ACID;(S)-2-hydroxysuccinicacid;bmse000238;MALIC ACID [HSDB];MALIC ACID, (L);(S)-(-)-Hydroxysuccinate;L-MALIC ACID [FHFI];(S)-hydroxy-Butanedioic acid;SCHEMBL256122;L-MALIC ACID [WHO-DD];MALIC ACID, L- [II];(-)-(s)-hydroxybutanedioic acid;DTXSID30273987;(2S)-(-)-hydroxybutanedioic acid;AMY40197;HY-Y1069;BDBM50510127;s6292;AKOS006346693;CS-W020132;MALIC ACID L-(-)-FORM [MI];L-(-)-Malic acid, BioXtra, >=95%;AS-18628;L-(-)-Malic acid, >=95% (titration);(-)-1-Hydroxy-1,2-ethanedicarboxylic acid;M0022;EN300-93424;C00149;L-(-)-Malic acid, purum, >=99.0% (T);L-(-)-Malic acid, ReagentPlus(R), >=99%;M-0850;35F9ECA9-BBE6-463D-BF3F-275FACC5D14E;L-(-)-Malic acid, SAJ special grade, >=99.0%;L-(-)-Malic acid, Vetec(TM) reagent grade, 97%;Q27104150;Z1201618618;(S)-(-)-2-Hydroxysuccinic acid, L-Hydroxybutanedioic acid;L-(-)-Malic acid, 97%, optical purity ee: 99% (GLC);L-(-)-Malic acid, certified reference material, TraceCERT(R);L-(-)-Malic acid, BioReagent, suitable for cell culture, suitable for insect cell culture;26999-59-7

Suppliers and Price of (2S)-2-Hydroxybutanedioic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
L-Malic acid 99+%
25g
$ 156.00

TRC
L-(-)-Malic acid
10g
$ 50.00

TCI Chemical
L-(-)-Malic Acid >98.0%(T)
25g
$ 24.00

TCI Chemical
L-(-)-Malic Acid >98.0%(T)
100g
$ 67.00

TCI Chemical
L-(-)-Malic Acid >98.0%(T)
500g
$ 210.00

SynQuest Laboratories
L-(-)-Malic acid 99%
10 kg
$ 792.00

SynQuest Laboratories
L-(-)-Malic acid 99%
2.5 kg
$ 288.00

SynQuest Laboratories
L-(-)-Malic acid 99%
1 kg
$ 200.00

Sigma-Aldrich
L-(-)-Malic acid for resolution of racemates for synthesis
1 kg
$ 197.02

Sigma-Aldrich
L-(?)-Malic acid BioReagent, suitable for cell culture, suitable for insect cell culture
100g
$ 143.00

Total 232 raw suppliers

Chemical Property of (2S)-2-Hydroxybutanedioic acid Edit

Chemical Property:

Appearance/Colour:clear colourless solution
Vapor Pressure:7.19E-05mmHg at 25°C
Melting Point:101-103 °C(lit.)
Refractive Index:-6.5 ° (C=10, Acetone)
Boiling Point:306.4 °C at 760 mmHg
PKA:(1) 3.46, (2) 5.10(at 25℃)
Flash Point:153.4 °C
PSA：94.83000
Density:1.641 g/cm³
LogP:-1.09340
Storage Temp.:Store at RT.
Solubility.:H2O: 0.5 M at 20 °C, clear, colorless
Water Solubility.:soluble
XLogP3:-1.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:134.02152329
Heavy Atom Count:9
Complexity:129

Purity/Quality:

99% ^*data from raw suppliers

L-Malic acid 99+% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-37/39

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Other Classes -> Organic Acids
Canonical SMILES:C(C(C(=O)O)O)C(=O)O
Isomeric SMILES:C([C@@H](C(=O)O)O)C(=O)O
Description L-Malic acid is nearly odorless (sometimes a faint, acrid odor) with a tart, acidic taste. It is nonpungent. May be prepared by hydration of maleic acid; by fermentation from sugars.
Uses L-Malic acid is used as a food additive, Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B. Intermediate in chemical synthesis. Chelating and buffering agent. Flavoring agent, flavor enhancer and acidulant in foods.

Technology Process of (2S)-2-Hydroxybutanedioic acid

There total 114 articles about (2S)-2-Hydroxybutanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 423170-79-0
2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxybutanedioic acid

: 636-61-3,78644-42-5
D-Malic acid

: 97-67-6,78644-42-5
(S)-Malic acid

Guidance literature:: 2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxybutanedioic acid; With sodium hydroxide; In water; for 24h;

With hydrogenchloride; In water; pH=1.2;
DOI:10.1002/cbdv.201100341