(Z)-(3S,5R)-2-(2-hydroxyethylidene)-3-(m-chlorobenzoyloxy)clavam

Base Information

• Chemical Name: (Z)-(3S,5R)-2-(2-hydroxyethylidene)-3-(m-chlorobenzoyloxy)clavam
• CAS No.: 71916-37-5
• Molecular Formula: C₁₄H₁₂ClNO₅
• Molecular Weight: 309.706
• Mol file: 71916-37-5.mol

Synonyms:(Z)-(3S,5R)-2-(2-hydroxyethylidene)-3-(m-chlorobenzoyloxy)clavam

Chemical Property of (Z)-(3S,5R)-2-(2-hydroxyethylidene)-3-(m-chlorobenzoyloxy)clavam

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-(3S,5R)-2-(2-hydroxyethylidene)-3-(m-chlorobenzoyloxy)clavam

There total 3 articles about (Z)-(3S,5R)-2-(2-hydroxyethylidene)-3-(m-chlorobenzoyloxy)clavam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.0%

→ (Z)-(3S,5R)-2-(2-hydroxyethylidene)-3-(m-chlorobenzoyloxy)clavam (71916-37-5)

Guidance literature:

Reference yield:

3-chloro-benzenecarboperoxoic acid (937-14-4) + clavulanic acid (58001-44-8) → (Z)-(3S,5R)-2-(2-hydroxyethylidene)-3-(m-chlorobenzoyloxy)clavam (71916-37-5)

Guidance literature:

With dicyclohexyl-carbodiimide; In 1,2-dimethoxyethane; dichloromethane; 1.) 0 deg C, 3 h, 2.) room temperature, 15 h;

Reference yield:

→ 3-Chloro-benzoic acid (S)-3-[2-hydroxy-eth-(Z)-ylidene]-7-oxo-4-oxa-1-aza-bicyclo[3.2.0]hept-2-yl ester (71916-37-5)

Guidance literature:

Clavulansaeure, Chlorperbenzoesaeure;

upstream raw materials:

3-chloro-benzenecarboperoxoic acid

clavulanic acid

Downstream raw materials:

(Z)-(3S,5R)-3-(m-chlorobenzoyloxy)-2-(2-phenylacetoxyethylidene)clavam