Changrolin

Base Information

Chemical Name:Changrolin
CAS No.:72063-47-9
Molecular Formula:C24H29 N5 O
Molecular Weight:403.527
Hs Code.:
UNII:XCP7AVW14B
DSSTox Substance ID:DTXSID10222397
Nikkaji Number:J39.455F
Wikidata:Q27293777
ChEMBL ID:CHEMBL26791
Mol file:72063-47-9.mol

Synonyms:4-(3',5'-bis(N-pyrrolidinyl)methyl)-(4'-hydroxyanilino)quinazoline;changrolin

Suppliers and Price of Changrolin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
CHANGROLIN 95.00%
5MG
$ 502.45

Total 4 raw suppliers

Chemical Property of Changrolin

Chemical Property:

Vapor Pressure:4.52E-12mmHg at 25°C
Boiling Point:535.2°C at 760 mmHg
Flash Point:277.5°C
PSA：64.52000
Density:1.294g/cm³
LogP:4.21940
XLogP3:4.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:403.23721057
Heavy Atom Count:30
Complexity:508

Purity/Quality:

99% ^*data from raw suppliers

CHANGROLIN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)CC2=CC(=CC(=C2O)CN3CCCC3)NC4=NC=NC5=CC=CC=C54

Technology Process of Changrolin

There total 3 articles about Changrolin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.3%

: 123-75-1
pyrrolidine

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 34923-98-3
4-(p-hydroxyphenyl)aminoquinazoline

: 72063-47-9
Changrolin

Guidance literature:: In ethanol; at 78 ℃; for 24h;

Reference yield:

: 5190-68-1
4-chloroquinazoline

: 72063-47-9
Changrolin

Guidance literature:: Multi-step reaction with 2 steps

1: ethyl acetate / 8 h / 78 °C

2: ethanol / 24 h / 78 °C

In ethanol; ethyl acetate;

Reference yield:

: 123-30-8
4-amino-phenol

: 72063-47-9
Changrolin

Guidance literature:: Multi-step reaction with 2 steps

1: ethyl acetate / 8 h / 78 °C

2: ethanol / 24 h / 78 °C

In ethanol; ethyl acetate;