C₂₄H₄₀O₃

Base Information

• Chemical Name: C₂₄H₄₀O₃
• CAS No.: 1402544-23-3
• Molecular Formula: C₂₄H₄₀O₃
• Molecular Weight: 376.58
• Mol file: 1402544-23-3.mol

Synonyms:C₂₄H₄₀O₃

Chemical Property of C₂₄H₄₀O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₄₀O₃

There total 6 articles about C₂₄H₄₀O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C21H34O4 (1402544-37-9) + tert-butylmagnesium chloride (677-22-5) → C24H40O3 (1402544-23-3)

Guidance literature:

C₂₁H₃₄O₄; With 2-chloro-4-picoline; trimethylsilyl trifluoromethanesulfonate; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

tert-butylmagnesium chloride; With copper(l) iodide; In tetrahydrofuran; at 0 ℃; for 3h; Inert atmosphere;

DOI:10.1002/adsc.201200290

Reference yield:

11-hydroxy-11-methyl-dodec-1-ene (34386-60-2) → C24H40O3 (1402544-23-3)

Guidance literature:

Multi-step reaction with 5 steps

1.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

2.1: ozone / dichloromethane / 3 h / -78 °C

3.1: sodium tetrahydroborate / methanol / 1 h / 20 °C

4.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 8 h / 20 °C / Inert atmosphere

5.1: 2-chloro-4-picoline; trimethylsilyl trifluoromethanesulfonate / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

5.2: 3 h / 0 °C / Inert atmosphere

With 2-chloro-4-picoline; dmap; sodium tetrahydroborate; trimethylsilyl trifluoromethanesulfonate; ozone; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1002/adsc.201200290

Reference yield:

C15H30O2 (1402544-34-6) → C24H40O3 (1402544-23-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: ozone / dichloromethane / 3 h / -78 °C

2.1: sodium tetrahydroborate / methanol / 1 h / 20 °C

3.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 8 h / 20 °C / Inert atmosphere

4.1: 2-chloro-4-picoline; trimethylsilyl trifluoromethanesulfonate / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

4.2: 3 h / 0 °C / Inert atmosphere

With 2-chloro-4-picoline; dmap; sodium tetrahydroborate; trimethylsilyl trifluoromethanesulfonate; ozone; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1002/adsc.201200290

upstream raw materials:

C₁₅H₃₀O₂

C₁₄H₂₈O₃

C₁₄H₃₀O₃

C₂₁H₃₄O₄