4-Methoxycarbonylmethoxy-piperidine-1-carboxylic acid benzyl ester

Base Information

• Chemical Name: 4-Methoxycarbonylmethoxy-piperidine-1-carboxylic acid benzyl ester
• CAS No.: 933477-82-8
• Molecular Formula: C₁₆H₂₁NO₅
• Molecular Weight: 307.346
• Mol file: 933477-82-8.mol

Synonyms:[(1-benzyloxycarbonylpiperidin-4-yl)oxy]acetic acid methyl ester

Chemical Property of 4-Methoxycarbonylmethoxy-piperidine-1-carboxylic acid benzyl ester

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

4-Methoxycarbonylmethoxy-piperidine-1-carboxylicacidbenzylester 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Methoxycarbonylmethoxy-piperidine-1-carboxylic acid benzyl ester

There total 1 articles about 4-Methoxycarbonylmethoxy-piperidine-1-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(benzyloxycarbonyl)-4-hydroxypiperidine (95798-23-5) + bromoacetic acid methyl ester (96-32-2) → [(1-benzyloxycarbonylpiperidin-4-yl)oxy]acetic acid methyl ester (933477-82-8)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 20 - 50 ℃; for 3h;

Reference yield:

[(1-benzyloxycarbonylpiperidin-4-yl)oxy]acetic acid methyl ester (933477-82-8) → 2-(1-[(benzyloxy)carbonyl]-4-piperidyloxy)acetic acid (162504-85-0)

Guidance literature:

[(1-benzyloxycarbonylpiperidin-4-yl)oxy]acetic acid methyl ester; With water; sodium hydroxide; In methanol; for 3h; Heating / reflux;

With hydrogenchloride; In water; at 20 ℃; pH=3;

upstream raw materials:

1-(benzyloxycarbonyl)-4-hydroxypiperidine

bromoacetic acid methyl ester

Downstream raw materials:

2-(1-[(benzyloxy)carbonyl]-4-piperidyloxy)acetic acid

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