Cyclohexylphenylacetic acid

Base Information

Chemical Name:Cyclohexylphenylacetic acid
CAS No.:3894-09-5
Molecular Formula:C14H18O2
Molecular Weight:218.296
Hs Code.:2916399090
European Community (EC) Number:223-443-3
NSC Number:60418
Nikkaji Number:J150.086D
Mol file:3894-09-5.mol

Synonyms:Cyclohexylphenylacetic acid;3894-09-5;2-cyclohexyl-2-phenylacetic acid;cyclohexyl(phenyl)acetic acid;alpha-Cyclohexyl-benzeneacetic Acid;alpha-Cyclohexylphenylacetic acid;alpha-Phenylcyclohexylacetic acid;.alpha.-Cyclohexylphenylacetic acid;a-Cyclohexylphenylacetic acid;cyclohexyl-phenylacetic acid;cyclohexyl-phenyl-acetic acid;SCHEMBL67219;2-cyclohexyl-2-phenylaceticacid;AAJLPPDFIRPBDA-UHFFFAOYSA-;LCZC00005;alpha -Cyclohexylphenylacetic acid;2-cyclohexyl-2-phenyl-acetic acid;NSC60418;EINECS 223-443-3;2-cyclohexyl-2-phenylacetic acidacid;MFCD00001477;NSC 60418;NSC-60418;AKOS022220971;Benzeneacetic acid, .alpha.-cyclohexyl-;C2812;D86449;EN300-5511768

Suppliers and Price of Cyclohexylphenylacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
α-Cyclohexyl-benzeneaceticAcid
5g
$ 330.00

TRC
α-Cyclohexyl-benzeneaceticAcid
1g
$ 110.00

TCI Chemical
alpha-Cyclohexylphenylacetic Acid >95.0%(GC)(T)
5g
$ 120.00

TCI Chemical
alpha-Cyclohexylphenylacetic Acid >95.0%(GC)(T)
1g
$ 41.00

SynQuest Laboratories
Cyclohexyl(phenyl)acetic acid 95%
25 g
$ 263.00

SynQuest Laboratories
Cyclohexyl(phenyl)acetic acid 95%
5 g
$ 56.00

Crysdot
2-Cyclohexyl-2-phenylaceticacid 97%
100g
$ 433.00

Chemenu
2-Cyclohexyl-2-phenylaceticacid 97%
100g
$ 409.00

Apolloscientific
Cyclohexyl(phenyl)aceticacid 95%
5g
$ 51.00

Apolloscientific
Cyclohexyl(phenyl)aceticacid 95%
25g
$ 238.00

Total 13 raw suppliers

Chemical Property of Cyclohexylphenylacetic acid

Chemical Property:

Appearance/Colour:grey crystalline powder
Vapor Pressure:1.34E-05mmHg at 25°C
Melting Point:148-152 °C
Refractive Index:1.5300 (estimate)
Boiling Point:353.3 °C at 760 mmHg
PKA:4.30±0.10(Predicted)
Flash Point:250.2 °C
PSA：37.30000
Density:1.11 g/cm³
LogP:3.43510
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:218.130679813
Heavy Atom Count:16
Complexity:225

Purity/Quality:

98%,99%, ^*data from raw suppliers

α-Cyclohexyl-benzeneaceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)C(C2=CC=CC=C2)C(=O)O
Uses α-Cyclohexyl-benzeneacetic Acid is a useful synthetic intermediate. It was used as one of the reactants to prepare phenylureidobenzazepinones as cholecystokinin-B receptor antagonists. It can also be used to synthesize benzimidazole derivatives as potent AMP-activated protein kinase activators.

Technology Process of Cyclohexylphenylacetic acid

There total 21 articles about Cyclohexylphenylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 103-82-2
phenylacetic acid

: 953-91-3
cyclohexyl tosylate

: 3894-09-5,51019-55-7
2-cyclohexyl-2-phenylacetic acid

Guidance literature:: phenylacetic acid; With lithium diethylamide; In tetrahydrofuran; at -78 ℃; for 0.5h;

cyclohexyl tosylate; In tetrahydrofuran; at 20 ℃; for 4h;
DOI:10.1055/s-2000-6323

Reference yield: 93.0%

: 4335-77-7,20585-34-6,20585-39-1,50896-04-3
cyclohexylmandelic acid

: 3894-09-5,51019-55-7
2-cyclohexyl-2-phenylacetic acid

Guidance literature:: With phosphonic Acid; methanesulfonic acid; sodium iodide; In water; at 95 ℃; for 48h; Inert atmosphere;
DOI:10.1021/jo2018087

Reference yield: 57.0%

: 5664-22-2
(+/-)-2-cyclohexyl-2-phenylacetaldehyde

: 712-50-5
Cyclohexyl phenyl ketone

: 3894-09-5,51019-55-7
2-cyclohexyl-2-phenylacetic acid

Guidance literature:: With iodosylbenzene; trifluoroborane diethyl ether; In dichloromethane; at 20 ℃; for 2h; Molecular sieve; Inert atmosphere;
DOI:10.1021/ol301675v