2,3-Bis(p-hydroxyphenyl)valeronitrile

Base Information

Chemical Name:2,3-Bis(p-hydroxyphenyl)valeronitrile
CAS No.:65-14-5
Molecular Formula:C₁₇H₁₇NO₂
Molecular Weight:267.327
Hs Code.:
DSSTox Substance ID:DTXSID90983550
Nikkaji Number:J36.575K
ChEMBL ID:CHEMBL463767

Synonyms:2,3-bis(4-hydroxyphenyl)pentanenitrile;SC-3402;2,3-Bis(p-hydroxyphenyl)valeronitrile;Valeronitrile, 2,3-bis(p-hydroxyphenyl)-;65-14-5;CHEMBL463767;DTXSID90983550;2,3-Bis(4-hydroxyphenyl)valeronitrile;2,3-bis(p-hydroxy-phenyl) valeronitrile;LS-161194

Suppliers and Price of 2,3-Bis(p-hydroxyphenyl)valeronitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2,3-Bis(p-hydroxyphenyl)valeronitrile

Chemical Property:

Vapor Pressure:9.84E-09mmHg at 25°C
Boiling Point:450.5°C at 760 mmHg
Flash Point:226.3°C
Density:1.192g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:267.125928785
Heavy Atom Count:20
Complexity:332

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C1=CC=C(C=C1)O)C(C#N)C2=CC=C(C=C2)O

Technology Process of 2,3-Bis(p-hydroxyphenyl)valeronitrile

There total 5 articles about 2,3-Bis(p-hydroxyphenyl)valeronitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 79568-15-3
2,3-Bis(4-methoxyphenyl)valeronitril

: 65-14-5,85628-82-6
rac-(2R,3S)-2,3-bis(4-hydroxyphenyl)pentanenitrile

Guidance literature:: With pyridine hydrochloride; at 210 ℃; for 5h;
DOI:10.1002/ardp.19833160316

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 65-14-5,85628-82-6
rac-(2R,3S)-2,3-bis(4-hydroxyphenyl)pentanenitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / C₂H₅ONa / ethanol / 5 h / Ambient temperature

2: 1.) Mg / 1.) ether, 2.) THF, reflux, 1 h; room temp., 20 h

3: 83 percent / pyridine hydrochloride / 5 h / 210 °C

With sodium ethanolate; pyridine hydrochloride; magnesium; In ethanol;
DOI:10.1002/ardp.19833160316

Reference yield:

: 104-47-2
p-methoxybenzylnitrile

: 65-14-5,85628-82-6
rac-(2R,3S)-2,3-bis(4-hydroxyphenyl)pentanenitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / C₂H₅ONa / ethanol / 5 h / Ambient temperature

2: 1.) Mg / 1.) ether, 2.) THF, reflux, 1 h; room temp., 20 h

3: 83 percent / pyridine hydrochloride / 5 h / 210 °C

With sodium ethanolate; pyridine hydrochloride; magnesium; In ethanol;
DOI:10.1002/ardp.19833160316