Technology Process of 3,5-bis(3-(4-(dodecyloxy)phenyl)-1,2,4-oxadiazol-5-yl)aniline
There total 6 articles about 3,5-bis(3-(4-(dodecyloxy)phenyl)-1,2,4-oxadiazol-5-yl)aniline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
5,5'-(5-nitro-1,3-phenylene)bis(3-(4-(dodecyloxy)phenyl)-1,2,4-oxadiazole);
With
tin(II) chloride dihdyrate;
In
ethanol; ethyl acetate;
for 4h;
Reflux;
With
water; sodium hydroxide;
In
ethanol; ethyl acetate;
for 2h;
pH=8;
Cooling with ice;
DOI:10.1016/j.tet.2011.10.019
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: thionyl chloride; N,N-dimethyl-formamide / 4 h / Reflux
2.1: pyridine / 24 h / Reflux
3.1: tin(II) chloride dihdyrate / ethanol; ethyl acetate / 4 h / Reflux
3.2: 2 h / pH 8 / Cooling with ice
With
pyridine; thionyl chloride; tin(II) chloride dihdyrate; N,N-dimethyl-formamide;
In
ethanol; ethyl acetate;
DOI:10.1016/j.tet.2011.10.019
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / butanone / 24 h / Reflux
2.1: hydroxylamine hydrochloride; potassium hydroxide / methanol; water / 24 h / Reflux
3.1: pyridine / 24 h / Reflux
4.1: tin(II) chloride dihdyrate / ethanol; ethyl acetate / 4 h / Reflux
4.2: 2 h / pH 8 / Cooling with ice
With
pyridine; tin(II) chloride dihdyrate; hydroxylamine hydrochloride; potassium carbonate; potassium hydroxide;
In
methanol; ethanol; water; ethyl acetate; butanone;
2.1: Thiemann reaction;
DOI:10.1016/j.tet.2011.10.019
