1-benzoyl-3-phenyl-1H-1,2,4-triazol-5-amine

Base Information

Chemical Name:1-benzoyl-3-phenyl-1H-1,2,4-triazol-5-amine
CAS No.:3357-34-4
Molecular Formula:C₁₅H₁₂N₄O
Molecular Weight:264.286
Hs Code.:
DSSTox Substance ID:DTXSID201262572

Synonyms:1-benzoyl-3-phenyl-1H-1,2,4-triazol-5-amine;SCHEMBL2554237;DTXSID201262572;HMS3464F14;CCG-157504;3357-34-4

Suppliers and Price of 1-benzoyl-3-phenyl-1H-1,2,4-triazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-benzoyl-3-phenyl-1H-1,2,4-triazol-5-amine

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:264.10111102
Heavy Atom Count:20
Complexity:337

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NN(C(=N2)N)C(=O)C3=CC=CC=C3

Technology Process of 1-benzoyl-3-phenyl-1H-1,2,4-triazol-5-amine

There total 4 articles about 1-benzoyl-3-phenyl-1H-1,2,4-triazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 98-88-4
benzoyl chloride

: 4922-98-9
3-phenyl-1H-1,2,4-triazol-5-amine

: 3357-34-4
(5-amino-3-phenyl-1H-1,2,4-triazol-1-yl)(phenyl)methanone

Guidance literature:: With pyridine; In tetrahydrofuran; at 0 - 20 ℃; for 4h;
DOI:10.1021/acs.jmedchem.0c01635

Reference yield:

: 613-94-5
benzoic acid hydrazide

: 3357-34-4
(5-amino-3-phenyl-1H-1,2,4-triazol-1-yl)(phenyl)methanone

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol; water / 24 h / Reflux

2: potassium hydroxide / ethanol; water / 2 h / Reflux

3: pyridine / tetrahydrofuran / 4 h / 0 - 20 °C

With pyridine; potassium hydroxide; In tetrahydrofuran; ethanol; water;
DOI:10.1021/acs.jmedchem.0c01635

Reference yield:

: 3679-92-3
N-benzamidoguanide

: 3357-34-4
(5-amino-3-phenyl-1H-1,2,4-triazol-1-yl)(phenyl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / ethanol; water / 2 h / Reflux

2: pyridine / tetrahydrofuran / 4 h / 0 - 20 °C

With pyridine; potassium hydroxide; In tetrahydrofuran; ethanol; water;
DOI:10.1021/acs.jmedchem.0c01635