(R)-N-(4-cyanophenyl)-2-hydroxy-2-((R)-4-(4-methoxybenzyl)-3-oxomorpholin-2-yl)aacetamide

Base Information

Chemical Name:(R)-N-(4-cyanophenyl)-2-hydroxy-2-((R)-4-(4-methoxybenzyl)-3-oxomorpholin-2-yl)aacetamide
CAS No.:1228774-39-7
Molecular Formula:C₂₁H₂₁N₃O₅
Molecular Weight:395.415
Hs Code.:

Synonyms:(R)-N-(4-cyanophenyl)-2-hydroxy-2-((R)-4-(4-methoxybenzyl)-3-oxomorpholin-2-yl)aacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-N-(4-cyanophenyl)-2-hydroxy-2-((R)-4-(4-methoxybenzyl)-3-oxomorpholin-2-yl)aacetamide

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Technology Process of (R)-N-(4-cyanophenyl)-2-hydroxy-2-((R)-4-(4-methoxybenzyl)-3-oxomorpholin-2-yl)aacetamide

There total 1 articles about (R)-N-(4-cyanophenyl)-2-hydroxy-2-((R)-4-(4-methoxybenzyl)-3-oxomorpholin-2-yl)aacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 1228774-38-6
(R)-2-hydroxy-2-((R)-4-(4-methoxybenzyl) 3-oxomorpholin-2-yl)acetic acid

: 873-74-5
4-Aminobenzonitrile

: 1228774-39-7
(R)-N-(4-cyanophenyl)-2-hydroxy-2-((R)-4-(4-methoxybenzyl)-3-oxomorpholin-2-yl)aacetamide

Guidance literature:: (R)-2-hydroxy-2-((R)-4-(4-methoxybenzyl) 3-oxomorpholin-2-yl)acetic acid; With bis(trichloromethyl) carbonate; pyrographite; In tetrahydrofuran; at 0 - 20 ℃;

4-Aminobenzonitrile; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

Reference yield:

: 67-56-1
methanol

: 1228774-39-7
(R)-N-(4-cyanophenyl)-2-hydroxy-2-((R)-4-(4-methoxybenzyl)-3-oxomorpholin-2-yl)aacetamide

: C₂₂H₂₅N₃O₆*ClH

Guidance literature:: methanol; (R)-N-(4-cyanophenyl)-2-hydroxy-2-((R)-4-(4-methoxybenzyl)-3-oxomorpholin-2-yl)aacetamide; With acetyl chloride; at 0 - 20 ℃;

With hydrogenchloride;