(4-(ethoxycarbonyl)phenyl)zinc chloride

Base Information

• Chemical Name: (4-(ethoxycarbonyl)phenyl)zinc chloride
• CAS No.: 261516-38-5
• Molecular Formula: C₉H₉ClO₂Zn
• Molecular Weight: 250.012
• Mol file: 261516-38-5.mol

Synonyms:(4-(ethoxycarbonyl)phenyl)zinc chloride

Chemical Property of (4-(ethoxycarbonyl)phenyl)zinc chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of (4-(ethoxycarbonyl)phenyl)zinc chloride

There total 2 articles about (4-(ethoxycarbonyl)phenyl)zinc chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-iodobenzoic acid ethyl ester (51934-41-9) + zinc(II) chloride (7646-85-7,24359-56-6) → (4-(ethoxycarbonyl)phenyl)zinc chloride (261516-38-5)

Guidance literature:

4-iodobenzoic acid ethyl ester; With TurboGrignard; In tetrahydrofuran; at -30 ℃; for 0.5h; Schlenk technique; Inert atmosphere;

zinc(II) chloride; In tetrahydrofuran; at 0 - 25 ℃; for 0.25h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.8b03787

Reference yield: 6.0%

ethyl 4-chlorobenzoate (7335-27-5) + zinc (7440-66-6) → (4-(ethoxycarbonyl)phenyl)zinc chloride (261516-38-5) + benzoic acid ethyl ester (93-89-0,99341-95-4) + diethyl biphenyl-4,4'-dicarboxylate (47230-38-6)

Guidance literature:

With trifluoroacetic acid; cobalt(II) bromide; zinc dibromide; In acetonitrile; the mixt. in CH3CN was stirred at room temp., then arylbromide was added, stirred at room temp.; GC analysis;

DOI:10.1021/ja0289494

Reference yield: 98.0%

(4-(ethoxycarbonyl)phenyl)zinc chloride (261516-38-5) + N-phenylthiophthalimide (14204-27-4) → 4-(phenylsulfanyl)benzoic acid ethyl ester (10129-07-4)

Guidance literature:

With copper(II) acetate monohydrate; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1002/chem.201806261

upstream raw materials:

ethyl 4-chlorobenzoate

zinc

4-iodobenzoic acid ethyl ester

zinc(II) chloride

Downstream raw materials:

ethyl 4-(1,1-difluoro-2-morpholino-2-oxoethyl)benzoate

4-(phenylsulfanyl)benzoic acid ethyl ester