3-Chloro-4-(4-chlorophenyl)-2-butanone

Base Information

Chemical Name:3-Chloro-4-(4-chlorophenyl)-2-butanone
CAS No.:50789-59-8
Molecular Formula:C₁₀H₁₀Cl₂O
Molecular Weight:217.095
Hs Code.:
European Community (EC) Number:653-167-2

Synonyms:3-chloro-4-(4-chlorophenyl)-2-butanone;SCHEMBL1036428;KKCOSJVILRLIBA-UHFFFAOYSA-N;AKOS022278816

Suppliers and Price of 3-Chloro-4-(4-chlorophenyl)-2-butanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-Chloro-4-(4-chlorophenyl)-2-butanone

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:216.0108703
Heavy Atom Count:13
Complexity:174

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C(CC1=CC=C(C=C1)Cl)Cl

Technology Process of 3-Chloro-4-(4-chlorophenyl)-2-butanone

There total 3 articles about 3-Chloro-4-(4-chlorophenyl)-2-butanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 134747-46-9
4-(4-chlorophenyl)-3-buten-2-ol

: 50789-59-8
3-chloro-4-(4-chlorophenyl)-2-butanone

Guidance literature:: With N-chloro-succinimide; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; In tetrahydrofuran; water; at 20 ℃; for 12h; regioselective reaction;
DOI:10.1021/cs501618h

Reference yield:

: 156909-45-4
C₁₀H₁₁ClO

: 50789-59-8
3-chloro-4-(4-chlorophenyl)-2-butanone

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / tetrahydrofuran; water / 1 h / 20 °C

2: bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; N-chloro-succinimide / tetrahydrofuran; water / 12 h / 20 °C

With N-chloro-succinimide; bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; toluene-4-sulfonic acid; In tetrahydrofuran; water;
DOI:10.1021/cs501618h

Reference yield:

: 106-47-8
4-chloro-aniline

: 78-94-4,25038-87-3
methyl vinyl ketone

: 50789-59-8
3-chloro-4-(4-chlorophenyl)-2-butanone

Guidance literature:: 4-chloro-aniline; methyl vinyl ketone; With tert.-butylnitrite; copper dichloride; In acetonitrile; at 20 ℃; for 0.5h;

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In diethyl ether; at 20 ℃; for 0.166667h;
DOI:10.1016/j.bmcl.2011.08.060