Tropigline

Base Information

Chemical Name:Tropigline
CAS No.:533-08-4
Molecular Formula:C13H21NO2
Molecular Weight:223.3139
Hs Code.:
European Community (EC) Number:207-810-5
UNII:75GK1SV4EI,5O258V0L5T
ChEMBL ID:CHEMBL2107196,CHEMBL2107120
DSSTox Substance ID:DTXSID601023601,DTXSID901023824
Metabolomics Workbench ID:44097
NCI Thesaurus Code:C152623,C152765
Nikkaji Number:J6.998A
Wikidata:Q105279861,Q27262615
Wikipedia:Tigloidine
Mol file:533-08-4.mol

Synonyms:Tropigline;tigloidin;Tigloidine;495-83-0;Tiglylpseudotropine;Tropiglinum;Tropintiglinat;Tropiglina;Tropyl 2,3-dimethylacrylate;533-08-4;Tigloyltropine;Tropigline [INN:BAN];UNII-5O258V0L5T;5O258V0L5T;3.beta.-Tigloyloxytropane;3alpha-Tropanyl (E)-2-methylcrotonat;75GK1SV4EI;[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (E)-2-methylbut-2-enoate;[(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (Z)-2-methylbut-2-enoate;Tigloidina;Tigloidinum;TIGLYLTROPEINE;2-Butenoic acid, 2-methyl-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester,[1a,3b(E),5a]-;Tigloidine [INN:BAN];Tigloidinum [INN-Latin];Tigloidina [INN-Spanish];UNII-75GK1SV4EI;3-tigloyloxytropane;EINECS 207-810-5;3alpha-Tigloyloxytropane;TIGLOIDINE [MI];TIGLOIDINE [INN];TROPIGLINE [INN];Tigloyl pseudotropine;Tiglyssin;3.alpha.-Tigloyloxytropane;TIGLOIDINE [WHO-DD];SCHEMBL932922;SCHEMBL2233976;CHEMBL2107120;CHEMBL2107196;UVHGSMZRSVGWDJ-LKQNJMEQSA-N;UVHGSMZRSVGWDJ-WJKWMCMVSA-N;DTXSID601023601;DTXSID901023824;HY-U00082;AKOS040740369;Tigloidine (3-beta-Tigloyloxytropane);CS-6695;Tropigline (3-alpha-Tigloyloxytropane);MS-23254;TIGLIC ACID 3.ALPHA.-TROPANYL ESTER;TIGLIC ACID ESTER WITH PSEUDOTROPINE;NS00094399;Q27262615;(E)-1.ALPHA.H,5.ALPHA.H-TROPAN-3.BETA.-OL 2-METHYLCROTONATE;(8-METHYL-8-AZABICYCLO(3.2.1)OCTAN-3-YL) (E)-2-METHYLBUT-2-ENOATE;2-METHYL-2-BUTENOIC ACID (1.ALPHA.,3.ALPHA.(E),5.ALPHA.0- 8-METHYL-8-AZABICYCLO(3.2.1)OCT-3-YL ESTER;CROTONIC ACID, 2-METHYL-, 1.ALPHA.H,5.ALPHA.H-TROPAN-3.ALPHA.-YL ESTER, (E)- 3.ALPHA.

Suppliers and Price of Tropigline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
Tigloidine ≥98%
5mg
$ 468.00

American Custom Chemicals Corporation
TROPIGLINE 95.00%
5MG
$ 503.44

Total 12 raw suppliers

Chemical Property of Tropigline

Chemical Property:

Melting Point:181.5-183 °C
Boiling Point:290.2±33.0 °C(Predicted)
PKA:10.03±0.40(Predicted)
PSA：29.54000
Density:1.06±0.1 g/cm3(Predicted)
LogP:2.05890
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:223.157228913
Heavy Atom Count:16
Complexity:297

Purity/Quality:

99% ^*data from raw suppliers

Tigloidine ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC=C(C)C(=O)OC1CC2CCC(C1)N2C
Isomeric SMILES:C/C=C(\C)/C(=O)OC1C[C@H]2CC[C@@H](C1)N2C

Technology Process of Tropigline

There total 3 articles about Tropigline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: