3-(1,3-dioxolan-2-yl)-N,N-bis(2-(diphenylphosphino)ethyl)propanamide

Base Information

• Chemical Name: 3-(1,3-dioxolan-2-yl)-N,N-bis(2-(diphenylphosphino)ethyl)propanamide
• CAS No.: 1246636-32-7
• Molecular Formula: C₃₄H₃₇NO₃P₂
• Molecular Weight: 569.62
• Mol file: 1246636-32-7.mol

Synonyms:3-(1,3-dioxolan-2-yl)-N,N-bis(2-(diphenylphosphino)ethyl)propanamide

Chemical Property of 3-(1,3-dioxolan-2-yl)-N,N-bis(2-(diphenylphosphino)ethyl)propanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(1,3-dioxolan-2-yl)-N,N-bis(2-(diphenylphosphino)ethyl)propanamide

There total 1 articles about 3-(1,3-dioxolan-2-yl)-N,N-bis(2-(diphenylphosphino)ethyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

3-(1,3-dioxolan-2-yl)propanoic acid (4388-56-1) + bis(2-(diphenylphosphino)ethyl)amine hydrochloride (66534-97-2) → 3-(1,3-dioxolan-2-yl)-N,N-bis(2-(diphenylphosphino)ethyl)propanamide (1246636-32-7)

Guidance literature:

3-(1,3-dioxolan-2-yl)propanoic acid; With triethylamine; isobutyl chloroformate; In dichloromethane; at -10 ℃;

bis(2-(diphenylphosphino)ethyl)amine hydrochloride; With triethylamine; In dichloromethane; at -10 - 20 ℃;

DOI:10.1002/anie.201002174

Reference yield: 72.0%

3-(1,3-dioxolan-2-yl)-N,N-bis(2-(diphenylphosphino)ethyl)propanamide (1246636-32-7) → N,N-bis(2-(diphenylphosphino)ethyl)-4-oxobutanamide

Guidance literature:

With toluene-4-sulfonic acid; In tetrahydrofuran; water; at 70 ℃; for 72h;

DOI:10.1002/anie.201002174

upstream raw materials:

3-(1,3-dioxolan-2-yl)propanoic acid

bis(2-(diphenylphosphino)ethyl)amine hydrochloride