4388-56-1 Usage
Uses
Used in Pharmaceutical Industry:
3-[1,3]Dioxolan-2-yl-propionic acid is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the molecular structure and properties of the final drug products.
Used in Organic Chemistry:
3-[1,3]Dioxolan-2-yl-propionic acid is used as a reagent or building block in organic chemistry for the creation of complex organic molecules, leveraging its unique structural features.
Used in Polymer Industry:
3-[1,3]Dioxolan-2-yl-propionic acid is used as a monomer in the manufacturing of polymers, where it can influence the polymer's characteristics such as solubility, stability, and reactivity.
Used as a Solvent:
3-[1,3]Dioxolan-2-yl-propionic acid is utilized as a solvent in various chemical processes, taking advantage of its ability to dissolve a range of substances and facilitate reactions.
Safety and Storage:
3-[1,3]Dioxolan-2-yl-propionic acid should be handled and stored in a cool, dry place, away from heat and sources of ignition to ensure safety. Adherence to proper safety precautions is essential when working with 3-[1,3]DIOXOLAN-2-YL-PROPIONIC ACID.
Check Digit Verification of cas no
The CAS Registry Mumber 4388-56-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,3,8 and 8 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4388-56:
(6*4)+(5*3)+(4*8)+(3*8)+(2*5)+(1*6)=111
111 % 10 = 1
So 4388-56-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H10O4/c7-5(8)1-2-6-9-3-4-10-6/h6H,1-4H2,(H,7,8)
4388-56-1Relevant academic research and scientific papers
Practical Gram-Scale Synthesis of Iboxamycin, a Potent Antibiotic Candidate
Mason, Jeremy D.,Myers, Andrew G.,Pote, Aditya R.,Terwilliger, Daniel W.
supporting information, p. 11019 - 11025 (2021/08/03)
A gram-scale synthesis of iboxamycin, an antibiotic candidate bearing a fused bicyclic amino acid residue, is presented. A pivotal transformation in the route involves an intramolecular hydrosilylation-oxidation sequence to set the ring-fusion stereocenters of the bicyclic scaffold. Other notable features of the synthesis include a high-yielding, highly diastereoselective alkylation of a pseudoephenamine amide, a convergent sp3-sp2 Negishi coupling, and a one-pot transacetalization-reduction reaction to form the target compound's oxepane ring. Implementation of this synthetic strategy has provided ample quantities of iboxamycin to allow for its in vivo profiling in murine models of infection.
LINCOSAMIDE ANTIBIOTICS AND USES THEREOF
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Paragraph 00378, (2021/11/26)
Provided are compounds of Formula (I) for the treatment of infectious and inflammatory diseases. The compounds described herein are lincosamides modified at the amino acid (southern) region. The compounds may have further modification at the C-7 position of the aminooctose (northern) region, thus distinguishing them from lincomycin and clindamycin. Also provided are methods for preparing the compounds, pharmaceutical compositions comprising the compounds, and methods of treating infectious diseases using the disclosed compounds.
