Technology Process of 1,3,5-[Cl(Et3P)2PdCC]3C6H3
There total 1 articles about 1,3,5-[Cl(Et3P)2PdCC]3C6H3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
HNEt2;
copper(l) chloride;
In
diethylamine;
under N2, standard Schlenk techniques; Pd complex dissolved in HNEt2 contg. CuCl; 0.26 equiv. of ligand added; stirred for 3 h at room temp.; filtered; solvent removed under reduced pressure; dissolved in CH2Cl2; washed (aq. NH4Cl, H2O); org. layer dried (anhyd. MgSO4); filtered; concd.; chromd. (basic Al2O3, CH2Cl2-light petroleum, CH2Cl2); recrystd. (benzene-n-pentane); elem. anal.;
- Guidance literature:
-
With
NEt3;
copper(l) chloride;
In
tetrahydrofuran; triethylamine;
under N2; Me3SiC3C6H4CCH in THF added dropwise to soln. of Pd complex inTHF and NEt3 contg. CuCl at 0°C; stirred for 3 h at 0°C; filtered; solvent removed from filtrate under reduced pressure; dissolved in CH2Cl2; washed (aq. NH4Cl, H2O); org. layer dried (anhyd. MgSO4); filtered; concd. under reduced pressure; chromd. (basic Al2O3, CH2Cl2-light petroleum, CH2Cl2);
- Guidance literature:
-
With
NEt3;
copper(l) chloride;
In
tetrahydrofuran; triethylamine;
under N2; PhCCH in THF added dropwise to soln. of Pd complex in THF and NEt3 contg. CuCl at 0°C; stirred for 3 h at 0°C; filtered; solvent removed from filtrate under reduced pressure; dissolved in CH2Cl2; washed (aq. NH4Cl, H2O); org. layer dried (anhyd. MgSO4); filtered; concd. under reduced pressure; chromd. (basic Al2O3, CH2Cl2-light petroleum, CH2Cl2);
