4-N-[(2,4-dimethytohenyl)-phosphonamidate methyl ester]-2-(4-bromo-phenyl)-thiophene

Base Information

Chemical Name:4-N-[(2,4-dimethytohenyl)-phosphonamidate methyl ester]-2-(4-bromo-phenyl)-thiophene
CAS No.:1243142-35-9
Molecular Formula:C₁₉H₁₉BrNO₂PS
Molecular Weight:436.309
Hs Code.:

Synonyms:4-N-[(2,4-dimethytohenyl)-phosphonamidate methyl ester]-2-(4-bromo-phenyl)-thiophene

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Chemical Property of 4-N-[(2,4-dimethytohenyl)-phosphonamidate methyl ester]-2-(4-bromo-phenyl)-thiophene

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Technology Process of 4-N-[(2,4-dimethytohenyl)-phosphonamidate methyl ester]-2-(4-bromo-phenyl)-thiophene

There total 1 articles about 4-N-[(2,4-dimethytohenyl)-phosphonamidate methyl ester]-2-(4-bromo-phenyl)-thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1243142-33-7
5-(4-bromo-phenyl)-thiophen-3-ylamine

: 1198089-62-1
(2,4-dimethyl-phenyl)-phosphonic acid methyl ester

: 1243142-35-9
4-N-[(2,4-dimethytohenyl)-phosphonamidate methyl ester]-2-(4-bromo-phenyl)-thiophene

Guidance literature:: (2,4-dimethyl-phenyl)-phosphonic acid methyl ester; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; Inert atmosphere;

5-(4-bromo-phenyl)-thiophen-3-ylamine; With lithium diisopropyl amide; In tetrahydrofuran; at -78 - 20 ℃;

Reference yield: 84.0%

: 98437-24-2
benzofuran-2-boronic acid

: 1243142-35-9
4-N-[(2,4-dimethytohenyl)-phosphonamidate methyl ester]-2-(4-bromo-phenyl)-thiophene

: 1243142-37-1
4-N-[(2,4-dimethylphenyl)-phosphonamidate methyl ester]-2-[(benzofuran-2-yl)-phenyl]-thiophene

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In water; N,N-dimethyl-formamide; at 80 ℃; for 3h; Inert atmosphere;