Technology Process of 6-(benzyloxy)quinazoline-7-amine
There total 6 articles about 6-(benzyloxy)quinazoline-7-amine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
hexamethylenetetramine; diethyl 4-(benzyloxy)-1,3-phenylenedicarbamate;
With
triethylamine;
at 100 ℃;
With
potassium hydroxide; potassium hexacyanoferrate(III);
In
ethanol; water;
for 4h;
- Guidance literature:
-
diethyl 4-(benzyloxy)-1,3-phenylenedicarbamate;
With
hexamethylenetetramine; trifluoroacetic acid;
for 1h;
Inert atmosphere;
Schlenk technique;
Reflux;
With
potassium hydroxide; potassium hexacyanoferrate(III);
In
ethanol; water;
for 4h;
Inert atmosphere;
Schlenk technique;
Reflux;
DOI:10.1016/j.ejmech.2014.07.027
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / acetonitrile / 0.5 h / 20 °C / Inert atmosphere; Schlenk technique
1.2: 8 h / 75 °C / Inert atmosphere; Schlenk technique
2.1: 10% Pt/activated carbon; hydrogen / methanol / 6 h / 20 °C / Inert atmosphere; Schlenk technique
3.1: triethylamine / tetrahydrofuran / 2 h / 20 °C / Inert atmosphere; Schlenk technique
4.1: hexamethylenetetramine; trifluoroacetic acid / 1 h / Inert atmosphere; Schlenk technique; Reflux
4.2: 4 h / Inert atmosphere; Schlenk technique; Reflux
With
hexamethylenetetramine; 10% Pt/activated carbon; hydrogen; potassium carbonate; triethylamine; trifluoroacetic acid;
In
tetrahydrofuran; methanol; acetonitrile;
DOI:10.1016/j.ejmech.2014.07.027