1,3-dipalmitoyl-2-(4-(bis(2-chloroethyl)amino)benzenebutanoyl)glycerol

Base Information

• Chemical Name: 1,3-dipalmitoyl-2-(4-(bis(2-chloroethyl)amino)benzenebutanoyl)glycerol
• CAS No.: 85763-07-1
• Molecular Formula: C49H85 Cl2 N O6
• Molecular Weight: 855.11
• Mol file: 85763-07-1.mol

Synonyms:1,3-dipalmitoyl-2-(4-(bis(2-chloroethyl)amino)benzenebutanoyl)glycerol

Chemical Property of 1,3-dipalmitoyl-2-(4-(bis(2-chloroethyl)amino)benzenebutanoyl)glycerol

Chemical Property:

• Vapor Pressure: 4.59E-26mmHg at 25°C
• Boiling Point: 806.7°C at 760 mmHg
• Flash Point: 441.7°C
• PSA: 82.14000
• Density: 1.02g/cm³
• LogP: 14.25410

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-dipalmitoyl-2-(4-(bis(2-chloroethyl)amino)benzenebutanoyl)glycerol

There total 3 articles about 1,3-dipalmitoyl-2-(4-(bis(2-chloroethyl)amino)benzenebutanoyl)glycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

hexadecanoic acid, 2-hydroxy-1,3-propanediyl ester (502-52-3) + chlorambucil (305-03-3) → 1,3-dipalmitoyl-2-[4-(bis(2-chloroethyl)amino)benzenebutanoyl]glycerol (85763-07-1)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 48h; Ambient temperature;

DOI:10.1021/jm00362a021

Reference yield:

chlorambucil (305-03-3) → 1,3-dipalmitoyl-2-[4-(bis(2-chloroethyl)amino)benzenebutanoyl]glycerol (85763-07-1)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / benzene / 0 - 4 °C

2: benzene / 72 h / Heating

With thionyl chloride; In benzene;

DOI:10.1021/jm00362a021

Reference yield:

hexadecanoic acid, 2-hydroxy-1,3-propanediyl ester (502-52-3) + chlorambucil chloride (17981-81-6) → 1,3-dipalmitoyl-2-[4-(bis(2-chloroethyl)amino)benzenebutanoyl]glycerol (85763-07-1)

Guidance literature:

In benzene; for 72h; Yield given; Heating;

DOI:10.1021/jm00362a021

upstream raw materials:

hexadecanoic acid, 2-hydroxy-1,3-propanediyl ester

chlorambucil chloride

chlorambucil