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17981-81-6

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17981-81-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 17981-81-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,9,8 and 1 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 17981-81:
(7*1)+(6*7)+(5*9)+(4*8)+(3*1)+(2*8)+(1*1)=146
146 % 10 = 6
So 17981-81-6 is a valid CAS Registry Number.

17981-81-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name γ-[p-N-Di(2-chloroethyl)aminophenyl]butyryl chloride

1.2 Other means of identification

Product number -
Other names 4-[4-[N,N-bis(2-chloroethyl)amino]phenyl]butyryl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17981-81-6 SDS

17981-81-6Relevant articles and documents

Semi-automatic synthesis, antiproliferative activity and DNA-binding properties of new netropsin and bis-netropsin analogues

Szerszenowicz, Jakub,Drozdowska, Danuta

, p. 11300 - 11315 (2014)

A general route for the semi-automatic synthesis of some new potential minor groove binders was established. Six four-numbered sub-libraries of new netropsin and bis-netropsin analogues have been synthesized using a Syncore Reactor. The structures of the

Synthesis and preliminary biological evaluation of a 99mTc-chlorambucil derivative as a potential tumor imaging agent

Lin, Jianguo,Qiu, Ling,Lv, Gaochao,Li, Ke,Wang, Wei,Liu, Guiqing,Zhao, Xueyu,Wang, Shanshan

, p. 116 - 123 (2017)

Technetium-99m-based radiopharmaceuticals have been used widely as diagnostic agents in the nuclear medicine. Chlorambucil (CLB) as one typical alkylating drug exhibits excellent inhibition effects against many human malignancies. To develop and explore a

Synthesis, molecular modelling, and antiproliferative and cytotoxic effects of carbocyclic derivatives of distamycin with chlorambucil moiety

Bartulewicz, Danuta,Bielawski, Krzysztof,Bielawska, Anna,Rozanski, Andrzej

, p. 461 - 467 (2001)

New carbocylic analogues of distamycin and netropsin with chlorambucil moieties 5-8 have been synthesised. Data from the ethidium displacement assay showed that these compounds bind in the minor groove of DNA. The observed reduced affinity to AT pairs and increased affinity towards GC sequences of the carbocyclic lexitropsins with chlorambucil moiety 5-8 in comparison with netropsin and distamycin was observed and rationalised by means of molecular modelling techniques. All of the compounds 5-8 showed antiproliferative and cytotoxic effects in the standard cell line of the mammalian tumour MCF-7.

1 - {3 - [To - double - (2 - chloroethyl) amino] amphetamine yl} carbamoyl -5 - eadm and its preparation and use

-

Paragraph 0126-0130, (2019/03/15)

The invention discloses a structure of the formula I of the antineoplastic compound: 1 - {3 - [to - double - (2 - chloroethyl) amino] amphetamine yl} carboxamido - 5 - Fluorouracil and its preparation method. The present invention of said pharmaceutical c

5' - Deoxy - 5 - fluoro - N - {4 - [double (2 - chloroethyl) amino] benzene ding acyl} cytidine and its preparation method and application

-

Paragraph 0113; 0115, (2018/04/20)

The invention discloses a medicine molecule with a structure as shown in a formula I which is described in the specificatioin, i.e., 5'-deoxy-5-fluoro-N-{4-[bis(2-chloroethyl)amino]benzobutyryl}cytidine, and a preparation method thereof. The medicine mole

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