Technology Process of Phenyl-thiocarbamic acid O-[(3S,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl] ester
There total 3 articles about Phenyl-thiocarbamic acid O-[(3S,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl] ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydride;
In
tetrahydrofuran;
for 0.5h;
- Guidance literature:
-
Cholestanol;
With
tetra-(n-butyl)ammonium iodide; sodium hydride;
In
tetrahydrofuran;
for 0.5h;
phenyl isothiocyanate;
In
tetrahydrofuran;
for 2h;
Further stages.;
DOI:10.1021/jm0004401
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 29 (unit not given) / sodium / hexamethylphosphoric acid triamide; 2-methyl-propan-2-ol / 0.5 h / Ambient temperature; other carbamates, thiocarbamates, xanthates investigated
2: 68 percent / NaH / tetrahydrofuran / 0.5 h
With
sodium; sodium hydride;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; tert-butyl alcohol;
