Technology Process of 1-(2-phenyl-ethynyl)-3,4-di-O-benzyl-D-glucal
There total 4 articles about 1-(2-phenyl-ethynyl)-3,4-di-O-benzyl-D-glucal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride; acetic acid;
In
tetrahydrofuran;
at 20 ℃;
for 24h;
DOI:10.1039/c0cc00586j
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium methylate; methanol / 20 °C
1.2: 20 °C
1.3: 20 °C
2.1: pyridinium chlorochromate / 1,2-dichloro-ethane / 6 h / 80 °C / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere
3.2: 2 h / -78 °C / Inert atmosphere
4.1: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 24 h / 20 °C
With
methanol; n-butyllithium; tetrabutyl ammonium fluoride; sodium methylate; acetic acid; pyridinium chlorochromate;
In
tetrahydrofuran; 1,2-dichloro-ethane;
DOI:10.1002/chem.201402149
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: pyridinium chlorochromate / 1,2-dichloro-ethane / 6 h / 80 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere
2.2: 2 h / -78 °C / Inert atmosphere
3.1: tetrabutyl ammonium fluoride; acetic acid / tetrahydrofuran / 24 h / 20 °C
With
n-butyllithium; tetrabutyl ammonium fluoride; acetic acid; pyridinium chlorochromate;
In
tetrahydrofuran; 1,2-dichloro-ethane;
DOI:10.1002/chem.201402149
