5'-nitro-4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl

Base Information

Chemical Name:5'-nitro-4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl
CAS No.:1229419-20-8
Molecular Formula:C₁₇H₁₆F₃N₃O₂
Molecular Weight:351.328
Hs Code.:

Synonyms:5'-nitro-4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl

Suppliers and Price of 5'-nitro-4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5'-nitro-4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl

Chemical Property:

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Technology Process of 5'-nitro-4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl

There total 1 articles about 5'-nitro-4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4548-45-2
2-chloro-5-nitropyridine

: 6652-16-0
4-(3-trifluoromethyl-phenyl)-piperidine hydrochloride

: 1229419-20-8
5'-nitro-4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 80 ℃; for 24h; Sealed tube;

Reference yield:

: 1229419-20-8
5'-nitro-4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl

: 1229419-19-5
4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-5'-ylamine

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethanol; for 2h; under 2585.81 Torr;

Reference yield:

: 1229419-20-8
5'-nitro-4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl

: 1229418-79-4
2-phenyl-5-trifluoromethyl-oxazole-4-carboxylic acid [4-(3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-5'-yl]-amide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / palladium 10% on activated carbon / ethanol / 2 h / 2585.81 Torr

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / 20 °C

With hydrogen; N-ethyl-N,N-diisopropylamine; palladium 10% on activated carbon; In ethanol; dichloromethane;