2-amino-5-(4-nitrophenyl)pentanoic acid

Base Information

Chemical Name:2-amino-5-(4-nitrophenyl)pentanoic acid
CAS No.:1206716-20-2
Molecular Formula:C₁₁H₁₄N₂O₄
Molecular Weight:238.243
Hs Code.:

Synonyms:2-amino-5-(4-nitrophenyl)pentanoic acid

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Chemical Property of 2-amino-5-(4-nitrophenyl)pentanoic acid

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Technology Process of 2-amino-5-(4-nitrophenyl)pentanoic acid

There total 6 articles about 2-amino-5-(4-nitrophenyl)pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 162357-99-5
2-acetylamino-2-[3-(4-nitrophenyl)propyl]malonic acid diethyl ester

: 1206716-20-2
2-amino-5-(4-nitrophenyl)pentanoic acid

Guidance literature:: With hydrogenchloride; In water; acetic acid; for 24h; Reflux;

Reference yield:

: 53712-77-9
1-bromo-3-(4-nitrophenyl)propane

: 1068-90-2
2-acetylaminomalonic acid diethyl ester

: 1206716-20-2
2-amino-5-(4-nitrophenyl)pentanoic acid

Guidance literature:: 2-acetylaminomalonic acid diethyl ester; With sodium ethanolate; In ethanol; at 50 ℃; for 1.66667h; Reflux;

1-bromo-3-(4-nitrophenyl)propane; In ethanol; for 108h; Reflux;

With hydrogenchloride; acetic acid; In water; for 24h; Reflux;
DOI:10.1039/c0cc05707j

Reference yield:

: 637-59-2
1-Bromo-3-phenylpropane

: 1206716-20-2
2-amino-5-(4-nitrophenyl)pentanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: nitric acid; acetic anhydride; acetic acid / -40 - 20 °C

2.1: sodium ethanolate / ethanol / 1.67 h / 50 °C / Reflux

2.2: 108 h / Reflux

2.3: 24 h / Reflux

With nitric acid; sodium ethanolate; acetic anhydride; acetic acid; In ethanol;
DOI:10.1039/c0cc05707j