Propanoic acid, 2-cyano-

Base Information

• Chemical Name: Propanoic acid, 2-cyano-
• CAS No.: 632-07-5
• Molecular Formula: C4H5 N O2
• Molecular Weight: 99.0892
• Hs Code.: 2926909090
• Mol file: 632-07-5.mol

Synonyms:Propionic acid,2-cyano- (6CI,7CI,8CI); (?à)-2-Cyanopropanoic acid; 2-Cyanopropanoic acid; 2-Cyanopropionic acid; NSC528442; a-Cyanopropionic acid

Chemical Property of Propanoic acid, 2-cyano-

Chemical Property:

• Vapor Pressure: 0.00178mmHg at 25°C
• Melting Point: 35°C
• Refractive Index: 1.4166 (estimate)
• Boiling Point: 271.7°Cat760mmHg
• PKA: 2.57±0.10(Predicted)
• Flash Point: 118.1°C
• PSA: 61.09000
• Density: 1.194g/cm³
• LogP: 0.23068
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

2-Cyanopropanoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propanoic acid, 2-cyano-

There total 7 articles about Propanoic acid, 2-cyano- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

ethyl 2-cyanopropionate (1572-99-2) → 2-cyanopropanoic acid (632-07-5)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; methanol; water; for 1h;

DOI:10.1002/anie.201503789

Reference yield:

potassium cyanide + potassium (RS)-2-chloropropionate → 2-cyanopropanoic acid (632-07-5)

Guidance literature:

With hydrogenchloride; In water; Large scale;

Reference yield:

potassium cyanide (151-50-8) → 2-cyanopropanoic acid (632-07-5)

Guidance literature:

With water;

upstream raw materials:

α-cyanomethylmalonic acid diethyl ester

ethyl 2-cyanopropionate

potassium cyanide

carbon dioxide

Downstream raw materials:

methyl 2-cyanopropionate

ethyl 2-cyanopropionate

6-amino-1,5-dimethylpyrimidine-2,4-(1H,3H)-dione

DL-3-aminoisobutyric acid