Technology Process of 1-(3-bromo-2-isobutoxypropyl)-4-chlorobenzene
There total 4 articles about 1-(3-bromo-2-isobutoxypropyl)-4-chlorobenzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
bromine; triphenylphosphine;
In
dichloromethane;
at 0 - 20 ℃;
for 24.5h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydrogen; zinc dibromide / palladium 10% on activated carbon / ethyl acetate / 42 h / 20 °C / 760.05 Torr
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
2.2: 4 h / 0 - 20 °C
3.1: triphenylphosphine; bromine / dichloromethane / 24.5 h / 0 - 20 °C
With
lithium aluminium tetrahydride; hydrogen; bromine; triphenylphosphine; zinc dibromide;
palladium 10% on activated carbon;
In
tetrahydrofuran; dichloromethane; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium tert-butylate / tetrahydrofuran / 0 - 20 °C
2.1: hydrogen; zinc dibromide / palladium 10% on activated carbon / ethyl acetate / 42 h / 20 °C / 760.05 Torr
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
3.2: 4 h / 0 - 20 °C
4.1: triphenylphosphine; bromine / dichloromethane / 24.5 h / 0 - 20 °C
With
lithium aluminium tetrahydride; potassium tert-butylate; hydrogen; bromine; triphenylphosphine; zinc dibromide;
palladium 10% on activated carbon;
In
tetrahydrofuran; dichloromethane; ethyl acetate;
