2-(3-formyl-4-isobutyloxy phenyl)-4-methyl-thiazole-5-carboxylic acid isobutyl ester

Base Information

Chemical Name:2-(3-formyl-4-isobutyloxy phenyl)-4-methyl-thiazole-5-carboxylic acid isobutyl ester
CAS No.:1312815-36-3
Molecular Formula:C₂₀H₂₅NO₄S
Molecular Weight:375.489
Hs Code.:

Synonyms:2-(3-formyl-4-isobutyloxy phenyl)-4-methyl-thiazole-5-carboxylic acid isobutyl ester

Suppliers and Price of 2-(3-formyl-4-isobutyloxy phenyl)-4-methyl-thiazole-5-carboxylic acid isobutyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Descyano-3-formylFebuxostatIsobutylEster
100mg
$ 1980.00

Total 5 raw suppliers

Chemical Property of 2-(3-formyl-4-isobutyloxy phenyl)-4-methyl-thiazole-5-carboxylic acid isobutyl ester

Chemical Property:

Boiling Point:512.1±60.0 °C(Predicted)
Density:1.148±0.06 g/cm3(Predicted)

Purity/Quality:

NLT 98% ^*data from raw suppliers

3-Descyano-3-formylFebuxostatIsobutylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Impurity of the drug Febuxostat (F229000).

Technology Process of 2-(3-formyl-4-isobutyloxy phenyl)-4-methyl-thiazole-5-carboxylic acid isobutyl ester

There total 2 articles about 2-(3-formyl-4-isobutyloxy phenyl)-4-methyl-thiazole-5-carboxylic acid isobutyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 78-77-3
Isobutyl bromide

: 1312815-35-2
2-(3-formyl-4-hydroxy phenyl)-4-methyl-thiazole-5-carboxylic acid

: 1312815-36-3
2-(3-formyl-4-isobutyloxy phenyl)-4-methyl-thiazole-5-carboxylic acid isobutyl ester

Guidance literature:: With potassium carbonate; potassium iodide; In dimethyl sulfoxide; at 75 - 80 ℃; for 7h;

Reference yield:

: 886501-78-6
2-(4-hydroxy phenyl)-4-methyl-thiazole-5-carboxylic acid

: 1312815-36-3
2-(3-formyl-4-isobutyloxy phenyl)-4-methyl-thiazole-5-carboxylic acid isobutyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: methanesulfonic acid / 6 h / 80 - 85 °C

1.2: 25 - 30 °C

2.1: potassium carbonate; potassium iodide / dimethyl sulfoxide / 7 h / 75 - 80 °C

With methanesulfonic acid; potassium carbonate; potassium iodide; In dimethyl sulfoxide;