C₁₂H₁₀NIO

Base Information

• Chemical Name: C₁₂H₁₀NIO
• CAS No.: 958889-00-4
• Molecular Formula: C₁₂H₁₀INO
• Molecular Weight: 311.122
• Mol file: 958889-00-4.mol

Synonyms:C₁₂H₁₀NIO

Chemical Property of C₁₂H₁₀NIO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₂H₁₀NIO

There total 1 articles about C₁₂H₁₀NIO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

3-hydroxymethylpyridin (100-55-0) + 2-Iodophenol (533-58-4) → C12H10NIO (958889-00-4)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1080/00397910701483944

Reference yield: 74.0%

C12H10NIO (958889-00-4) + methyl iodide (74-88-4) → C13H13NIO1(1+)*I(1-)

Guidance literature:

In dichloromethane; at 20 ℃; for 24h;

DOI:10.1080/00397910701483944

Reference yield: 62.0%

C12H10NIO (958889-00-4) + benzyl bromide (100-39-0) → C19H17NIO1(1+)*Br(1-)

Guidance literature:

In dichloromethane; at 20 ℃; for 48h;

DOI:10.1080/00397910701483944

upstream raw materials:

3-hydroxymethylpyridin

2-Iodophenol

Downstream raw materials:

4-[(2-iodophenoxy)methyl]pyridine

2-Iodophenol

N-benzyl-5-methylene-1,2,5,6-tetrahydropyridine