C₃₁H₄₂O₇Si

Base Information

• Chemical Name: C₃₁H₄₂O₇Si
• CAS No.: 950849-16-8
• Molecular Formula: C₃₁H₄₂O₇Si
• Molecular Weight: 554.756
• Mol file: 950849-16-8.mol

Synonyms:C₃₁H₄₂O₇Si

Chemical Property of C₃₁H₄₂O₇Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₁H₄₂O₇Si

There total 1 articles about C₃₁H₄₂O₇Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-dimethoxy-propane (77-76-9) + (3S,3aR,4S,6S,6aS,8S,9R,9aR,9bS)-8-(tert-Butyl-diphenyl-silanyloxy)-3,3a-dihydroxy-4,6-bis-methoxymethoxy-3,6,9-trimethyl-decahydro-azuleno[4,5-b]furan-2-one (663605-99-0) → C31H42O7Si (950849-16-8) + (2aS,5aS,7S,7aS,9S,10R,10aR,10bS,10cR)-9-(tert-Butyl-diphenyl-silanyloxy)-7,10c-dihydroxy-2a,4,4,7,10-pentamethyl-decahydro-1,3,5-trioxa-benzo[cd]cyclopenta[h]azulen-2-one (663606-00-6)

Guidance literature:

With Amberlyst 15; In acetone; at 20 ℃; for 48h;

DOI:10.1002/chem.200700302

Reference yield:

C31H42O7Si (950849-16-8) → thiapsigargin (123269-03-4,67526-95-8)

Guidance literature:

Multi-step reaction with 16 steps

1.1: Amberlyst 15 / acetone / 48 h / 20 °C

2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 96 h / 20 °C

3.1: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 1.5 h / 20 °C

4.1: triethylamine / N,N-dimethyl-formamide / 43 h / 130 °C

5.1: 3,3-dimethyldioxirane / dichloromethane / -78 - 20 °C

6.1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 24 h / 20 °C

7.1: lithium hexamethyldisilazane / tetrahydrofuran / 2 h / -13 - -12 °C

7.2: 13 / 0.5 h / -95 - -90 °C

8.1: oxygen; ozone / dichloromethane / -78 °C

9.1: diisopropylamine / dichloromethane / -78 - 20 °C

10.1: zinc borohydride / diethyl ether / 0.5 h / -29 °C

10.2: tetrabutylammonium fluoride / 2; 13 / 0.5 h / 20 °C

11.1: sodium hydrogencarbonate / toluene / 42 h / 80 °C

12.1: n-butanethiol; potassium carbonate; magnesium bromide / diethyl ether / 0.5 h / 20 °C

13.1: dmap / dichloromethane / 1 h / 20 °C

14.1: toluene-4-sulfonic acid / 1.75 h / 20 °C

15.1: hydrogenchloride / methanol / 0.75 h / 45 °C

16.1: dichloromethane / 1.25 h / 20 °C

With hydrogenchloride; dmap; Amberlyst 15; n-butanethiol; zinc borohydride; tetrabutyl ammonium fluoride; oxygen; 3,3-dimethyldioxirane; sodium hydrogencarbonate; potassium carbonate; Dess-Martin periodane; toluene-4-sulfonic acid; ozone; triethylamine; diisopropylamine; N-ethyl-N,N-diisopropylamine; magnesium bromide; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide; acetone; toluene;

DOI:10.1002/chem.200700302

Reference yield:

C31H42O7Si (950849-16-8) + 2,2-dimethoxy-propane (77-76-9) → (2aS,5aS,7S,7aS,9S,10R,10aR,10bS,10cR)-9-(tert-Butyl-diphenyl-silanyloxy)-7,10c-dihydroxy-2a,4,4,7,10-pentamethyl-decahydro-1,3,5-trioxa-benzo[cd]cyclopenta[h]azulen-2-one (663606-00-6)

Guidance literature:

With Amberlyst 15; In acetone; at 20 ℃; for 48h;

DOI:10.1002/chem.200700302

upstream raw materials:

2,2-dimethoxy-propane

(3S,3aR,4S,6S,6aS,8S,9R,9aR,9bS)-8-(tert-Butyl-diphenyl-silanyloxy)-3,3a-dihydroxy-4,6-bis-methoxymethoxy-3,6,9-trimethyl-decahydro-azuleno[4,5-b]furan-2-one

Downstream raw materials:

(2aS,5aS,7S,7aS,9S,10R,10aR,10bS,10cR)-9-(tert-Butyl-diphenyl-silanyloxy)-7,10c-dihydroxy-2a,4,4,7,10-pentamethyl-decahydro-1,3,5-trioxa-benzo[cd]cyclopenta[h]azulen-2-one

C₃₆H₆₀O₉SeSi₃

thiapsigargin

trilobolide