5-(ALLYLOXY)-1,2,3-TRIMETHOXYBENZENE

Base Information

• Chemical Name: 5-(ALLYLOXY)-1,2,3-TRIMETHOXYBENZENE
• CAS No.: 150571-99-6
• Molecular Formula: C₁₂H₁₆O₄
• Molecular Weight: 224.257
• Mol file: 150571-99-6.mol

Synonyms:1-(allyloxy)-3,4,5-trimethoxybenzene

Chemical Property of 5-(ALLYLOXY)-1,2,3-TRIMETHOXYBENZENE

Chemical Property:

• Boiling Point: 316.8±37.0 °C(Predicted)
• Density: 1.050±0.06 g/cm3(Predicted)

Purity/Quality:

5-(ALLYLOXY)-1,2,3-TRIMETHOXYBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(ALLYLOXY)-1,2,3-TRIMETHOXYBENZENE

There total 4 articles about 5-(ALLYLOXY)-1,2,3-TRIMETHOXYBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3,4,5-trimethoxyphenol (642-71-7) + allyl bromide (106-95-6) → 1-(allyloxy)-3,4,5-trimethoxybenzene (150571-99-6)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 23 ℃; for 1h;

DOI:10.1080/00397919908086606

Reference yield: 89.0%

3,4,5-trimethoxyphenol (642-71-7) + 3-chloroprop-1-ene (107-05-1) → 1-(allyloxy)-3,4,5-trimethoxybenzene (150571-99-6)

Guidance literature:

3,4,5-trimethoxyphenol; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.333333h; Inert atmosphere;

3-chloroprop-1-ene; In N,N-dimethyl-formamide; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tetlet.2020.151995

Reference yield: 34.0%

3,4,5-trimethoxyphenol (642-71-7) → 1-(allyloxy)-3,4,5-trimethoxybenzene (150571-99-6)

Guidance literature:

With potassium carbonate; In acetone;

DOI:10.1039/b101837j

upstream raw materials:

3,4,5-trimethoxyphenol

allyl bromide

3-chloroprop-1-ene

Refernces

• 1、 Hui, Zi,Jiang, Songwei,Qi, Xiang,Ye, Xiang-Yang,Xie, Tian. "Investigating the microwave-accelerated Claisen rearrangement of allyl aryl ethers: Scope of the catalysts, solvents, temperatures, and substrates". supporting information. . Retrieved 2020/05/18.
• 2、 So, Won Youn,Jeong, Im Eom. "Facile construction of the benzofuran and chromene ring systems via Pd II-catalyzed oxidative cyclization". . p. 3355 - 3358. Retrieved 2007/10/03.