C₉H₁₁N*ClH

Base Information

• Chemical Name: C₉H₁₁N*ClH
• CAS No.: 1164111-44-7
• Molecular Formula: C₉H₁₁N*ClH
• Molecular Weight: 169.654
• Mol file: 1164111-44-7.mol

Synonyms:C₉H₁₁N*ClH

Chemical Property of C₉H₁₁N*ClH

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₉H₁₁N*ClH

There total 1 articles about C₉H₁₁N*ClH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyllithium (917-54-4) + 3-Methylbenzonitrile (620-22-4) → C9H11N*ClH (1164111-44-7)

Guidance literature:

methyllithium; 3-Methylbenzonitrile; In tetrahydrofuran; diethyl ether; at -78 ℃; Inert atmosphere;

With methanol; In tetrahydrofuran; diethyl ether; at 20 ℃; Inert atmosphere;

With hydrogenchloride; In diethyl ether; tert-butyl methyl ether;

DOI:10.1021/ja903319r

Reference yield: 95.0%

C9H11N*ClH (1164111-44-7) → C9H13N*ClH

Guidance literature:

With bis(1,5-cyclooctadiene)diiridium(I) dichloride; 1,1'-bis[(S)-4,5-dihydro-3H-binaphtho[2,1-c:1',2'-e]phosphino]ferrocene; hydrogen; In methanol; dichloromethane; at 20 ℃; for 20h; under 7600.51 Torr; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1021/ja903319r

Reference yield: 94.0%

C9H11N*ClH (1164111-44-7) → (S)-1-(m-tolyl)ethan-1-amine hydrochloride (1630984-18-7)

Guidance literature:

With 2,6-bis(3,5-bis(3,7-bis(trifluoromethyl)naphthalen-1-yl)phenyl)-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide; di-tert-butyl 1,4-dihydro-2,6-dimethyl-3,5-pyridine-dicarboxylate; In tert-butyl methyl ether; methyl cyclohexane; at 20 ℃; for 24h; enantioselective reaction; Inert atmosphere; Molecular sieve;

DOI:10.1055/s-0040-1706413

upstream raw materials:

methyllithium

3-Methylbenzonitrile

Downstream raw materials:

(S)-1-(m-tolyl)ethan-1-amine hydrochloride

Refernces