ethyl (methyl 4-O-benzyl-2,3-O-isopropylidene-6,7-dideoxy-α-D-manno-octo-6E-enopyranosid)uronate

Base Information

Chemical Name:ethyl (methyl 4-O-benzyl-2,3-O-isopropylidene-6,7-dideoxy-α-D-manno-octo-6E-enopyranosid)uronate
CAS No.:740840-76-0
Molecular Formula:C₂₁H₂₈O₇
Molecular Weight:392.449
Hs Code.:

Synonyms:ethyl (methyl 4-O-benzyl-2,3-O-isopropylidene-6,7-dideoxy-α-D-manno-octo-6E-enopyranosid)uronate

Suppliers and Price of ethyl (methyl 4-O-benzyl-2,3-O-isopropylidene-6,7-dideoxy-α-D-manno-octo-6E-enopyranosid)uronate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl (methyl 4-O-benzyl-2,3-O-isopropylidene-6,7-dideoxy-α-D-manno-octo-6E-enopyranosid)uronate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl (methyl 4-O-benzyl-2,3-O-isopropylidene-6,7-dideoxy-α-D-manno-octo-6E-enopyranosid)uronate

There total 5 articles about ethyl (methyl 4-O-benzyl-2,3-O-isopropylidene-6,7-dideoxy-α-D-manno-octo-6E-enopyranosid)uronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-39-0
benzyl bromide

: 740840-76-0
ethyl (methyl 4-O-benzyl-2,3-O-isopropylidene-6,7-dideoxy-α-D-manno-octo-6E-enopyranosid)uronate

Guidance literature:: Multi-step reaction with 4 steps

1: 94 percent / NaH; HMPA; TBAI / tetrahydrofuran / 2 h / 23 °C

2: TBAF / tetrahydrofuran / 2 h / 23 °C

3: (COCl)2; DMSO; Et₃N / CH₂Cl₂ / -78 - 23 °C

4: 503 mg / CH₂Cl₂ / 5 h / 23 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; oxalyl dichloride; tetrabutyl ammonium fluoride; tetra-(n-butyl)ammonium iodide; sodium hydride; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; dichloromethane; 3: Swern oxidation / 4: Wittig reaction;
DOI:10.1002/anie.200353478

Reference yield:

: 82185-79-3
methyl 4-O-benzyl-2,3-O-isopropylidene-α-D-mannopyranoside

: 740840-76-0
ethyl (methyl 4-O-benzyl-2,3-O-isopropylidene-6,7-dideoxy-α-D-manno-octo-6E-enopyranosid)uronate

Guidance literature:: Multi-step reaction with 2 steps

1: (COCl)2; DMSO; Et₃N / CH₂Cl₂ / -78 - 23 °C

2: 503 mg / CH₂Cl₂ / 5 h / 23 °C

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; 1: Swern oxidation / 2: Wittig reaction;
DOI:10.1002/anie.200353478

Reference yield:

: 131089-35-5
methyl 6-O-tert-butyldiphenylsilyl-2,3-O-isopropylidene-α-D-mannopyranoside

: 740840-76-0
ethyl (methyl 4-O-benzyl-2,3-O-isopropylidene-6,7-dideoxy-α-D-manno-octo-6E-enopyranosid)uronate

Guidance literature:: Multi-step reaction with 4 steps

1: 94 percent / NaH; HMPA; TBAI / tetrahydrofuran / 2 h / 23 °C

2: TBAF / tetrahydrofuran / 2 h / 23 °C

3: (COCl)2; DMSO; Et₃N / CH₂Cl₂ / -78 - 23 °C

4: 503 mg / CH₂Cl₂ / 5 h / 23 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; oxalyl dichloride; tetrabutyl ammonium fluoride; tetra-(n-butyl)ammonium iodide; sodium hydride; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; dichloromethane; 3: Swern oxidation / 4: Wittig reaction;
DOI:10.1002/anie.200353478