2,4-Quinazolinediamine, 5-phenoxy-

Base Information

Chemical Name:2,4-Quinazolinediamine, 5-phenoxy-
CAS No.:123241-96-3
Molecular Formula:C₁₄H₁₂N₄O
Molecular Weight:252.275
Hs Code.:
ChEMBL ID:CHEMBL343286
DSSTox Substance ID:DTXSID70877428
Nikkaji Number:J272.202J
Wikidata:Q82859229

Synonyms:123241-96-3;GNF-PF-4916;2,4-Quinazolinediamine, 5-phenoxy-;CHEMBL343286;SCHEMBL6485667;DTXSID70877428;2,4-DIAMINOQUINAZOLINE,5-PHENOXY

Suppliers and Price of 2,4-Quinazolinediamine, 5-phenoxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,4-Quinazolinediamine, 5-phenoxy-

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:252.10111102
Heavy Atom Count:19
Complexity:295

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)OC2=CC=CC3=C2C(=NC(=N3)N)N

Technology Process of 2,4-Quinazolinediamine, 5-phenoxy-

There total 6 articles about 2,4-Quinazolinediamine, 5-phenoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 123241-47-4
2-phenoxy-6-aminobenzonitrile

: 29671-92-9
chloroformamidine hydrochloride

: 123241-96-3
5-phenoxyquinazoline-2,4-diamine

Guidance literature:: In diethylene glycol dimethyl ether; at 130 - 140 ℃; for 3h;
DOI:10.1021/jm00163a067

Reference yield:

: 35213-00-4
2,6-dinitrobenzonitrile

: 123241-96-3
5-phenoxyquinazoline-2,4-diamine

Guidance literature:: Multi-step reaction with 3 steps

1: 50 percent / potassium carbonate / dimethylformamide / 24 h / Heating

2: 37 percent / tin(II) chloride dihydrate, glacial acetic acid, concentrated hydrochloric acid / 4.5 h / Ambient temperature

3: 50 percent / bis-(2-methoxy-ethyl) ether / 3 h / 130 - 140 °C

With hydrogenchloride; potassium carbonate; acetic acid; tin(ll) chloride; In diethylene glycol dimethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jm00163a067

Reference yield:

: 123241-37-2
2-nitro-6-phenoxybenzonitrile

: 123241-96-3
5-phenoxyquinazoline-2,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 37 percent / tin(II) chloride dihydrate, glacial acetic acid, concentrated hydrochloric acid / 4.5 h / Ambient temperature

2: 50 percent / bis-(2-methoxy-ethyl) ether / 3 h / 130 - 140 °C

With hydrogenchloride; acetic acid; tin(ll) chloride; In diethylene glycol dimethyl ether;
DOI:10.1021/jm00163a067