Ethyl trans-3-phenyl-2-propenyl ketone

Base Information

• Chemical Name: Ethyl trans-3-phenyl-2-propenyl ketone
• CAS No.: 140462-87-9
• Molecular Formula: C₁₂H₁₄O
• Molecular Weight: 174.243
• Mol file: 140462-87-9.mol

Synonyms:Ethyl trans-3-phenyl-2-propenyl ketone

Chemical Property of Ethyl trans-3-phenyl-2-propenyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of Ethyl trans-3-phenyl-2-propenyl ketone

There total 6 articles about Ethyl trans-3-phenyl-2-propenyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-penten-3-one (1629-58-9) + benzaldehyde (100-52-7) → Ethyl trans-3-phenyl-2-propenyl ketone (140462-87-9)

Guidance literature:

4-penten-3-one; benzaldehyde; With indium(III) chloride; In tetrahydrofuran; water; at 20 ℃; for 8h;

With hydrogenchloride; In tetrahydrofuran; water; for 0.5h;

DOI:10.1002/anie.201703764

Reference yield: 78.0%

carbon monoxide (201230-82-2) + cinnamyl benzoate (50555-04-9) + diethylzinc (557-20-0) → Ethyl trans-3-phenyl-2-propenyl ketone (140462-87-9)

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In hexane; toluene; at 0 ℃; for 24h;

DOI:10.1021/jo00110a047

Reference yield: 45.0%

trans-styrylacetic acid (2243-53-0,59744-46-6,1914-58-5) + ethylmagnesium bromide (925-90-6) → Ethyl trans-3-phenyl-2-propenyl ketone (140462-87-9)

Guidance literature:

trans-styrylacetic acid; With 2,3-dihydro-2H-furan; methanesulfonic acid; In dichloromethane; at -20 ℃; for 4h; Cooling with ice;

ethylmagnesium bromide; In tetrahydrofuran; dichloromethane; at -20 - 20 ℃; for 18h; Inert atmosphere;

DOI:10.1021/ol201378w

upstream raw materials:

carbon monoxide

cinnamyl benzoate

diethylzinc

4-penten-3-one

Downstream raw materials:

2-ethyl-5-phenylfuran