1-(1,1-dimethyl-1-silaethoxy)-3-methylcyclohex-2-ene-1-carbonitrile

Base Information

• Chemical Name: 1-(1,1-dimethyl-1-silaethoxy)-3-methylcyclohex-2-ene-1-carbonitrile
• CAS No.: 615265-46-8
• Molecular Formula: C₁₁H₁₉NOSi
• Molecular Weight: 209.363
• Mol file: 615265-46-8.mol

Synonyms:1-(1,1-dimethyl-1-silaethoxy)-3-methylcyclohex-2-ene-1-carbonitrile

Chemical Property of 1-(1,1-dimethyl-1-silaethoxy)-3-methylcyclohex-2-ene-1-carbonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(1,1-dimethyl-1-silaethoxy)-3-methylcyclohex-2-ene-1-carbonitrile

There total 1 articles about 1-(1,1-dimethyl-1-silaethoxy)-3-methylcyclohex-2-ene-1-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-methylcyclohexen-2-one (1193-18-6) + trimethylsilyl cyanide (7677-24-9) → 1-(1,1-dimethyl-1-silaethoxy)-3-methylcyclohex-2-ene-1-carbonitrile (615265-46-8)

Guidance literature:

With zinc(II) iodide; In dichloromethane; at 0 ℃; for 0.666667h;

DOI:10.1021/jo0345291

Reference yield: 55.0%

dimethyl sulfoxide (67-68-5,8070-53-9) + 1-(1,1-dimethyl-1-silaethoxy)-3-methylcyclohex-2-ene-1-carbonitrile (615265-46-8) → 3-methyl-3-methylsulfanylmethoxy-cyclohex-1-enecarbonitrile (615265-49-1)

Guidance literature:

dimethyl sulfoxide; With acetic anhydride;

1-(1,1-dimethyl-1-silaethoxy)-3-methylcyclohex-2-ene-1-carbonitrile; at 20 ℃; for 40h;

DOI:10.1021/jo0345291

Reference yield:

1-(1,1-dimethyl-1-silaethoxy)-3-methylcyclohex-2-ene-1-carbonitrile (615265-46-8) → 3-hydroxy-3-methylcyclohex-1-ene-1-carbonitrile (450406-20-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: acetic anhydride

1.2: 55 percent / 40 h / 20 °C

2.1: 92 percent / mercuric chloride / acetonitrile; H₂O / 8 h

With acetic anhydride; mercury dichloride; In water; acetonitrile;

DOI:10.1021/jo0345291

upstream raw materials:

3-methylcyclohexen-2-one

trimethylsilyl cyanide

Downstream raw materials:

3-methyl-3-methylsulfanylmethoxy-cyclohex-1-enecarbonitrile

3-hydroxy-3-methylcyclohex-1-ene-1-carbonitrile

(1SR,5RS,6SR)-5-hydroxy-5-methyl-7-methylidenebicyclo[4.3.0]nonane-1-carbonitrile