3β-((3-carboxypropanoyl)oxy)olean-12-en-28-oic acid benzyl ester

Base Information

• Chemical Name: 3β-((3-carboxypropanoyl)oxy)olean-12-en-28-oic acid benzyl ester
• CAS No.: 1043913-97-8
• Molecular Formula: C₄₁H₅₈O₆
• Molecular Weight: 646.908
• Mol file: 1043913-97-8.mol

Synonyms:3β-((3-carboxypropanoyl)oxy)olean-12-en-28-oic acid benzyl ester

Chemical Property of 3β-((3-carboxypropanoyl)oxy)olean-12-en-28-oic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3β-((3-carboxypropanoyl)oxy)olean-12-en-28-oic acid benzyl ester

There total 7 articles about 3β-((3-carboxypropanoyl)oxy)olean-12-en-28-oic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

succinic acid anhydride (108-30-5) + oleanolic acid benzyl ester (303114-51-4) → 3β-((3-carboxypropanoyl)oxy)olean-12-en-28-oic acid benzyl ester (1043913-97-8)

Guidance literature:

With pyridine; dmap; Reflux;

DOI:10.1016/j.ejmech.2016.09.098

Reference yield:

benzyl chloride (100-44-7) + 3β-[3-(carboxyl)propionyloxy]-olean-12-en-28-oic acid (4847-30-7) → 3β-((3-carboxypropanoyl)oxy)olean-12-en-28-oic acid benzyl ester (1043913-97-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 55 ℃; for 4h;

DOI:10.1039/c6ra18879f

Reference yield:

Oleanolic acid (508-02-1) → 3β-((3-carboxypropanoyl)oxy)olean-12-en-28-oic acid benzyl ester (1043913-97-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 55 °C

2: pyridine / 24 h / 20 °C

With pyridine; potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1016/j.ejmech.2013.12.049

upstream raw materials:

succinic acid anhydride

oleanolic acid benzyl ester

Oleanolic acid

benzyl chloride

Downstream raw materials:

28-(benzyloxy)-28-oxoolean-12-en-3-yl 1-methyl-3-{[5-oxido-4-(phenylsulfonyl)-1,2,5-oxadiazol-3-yl]oxy}propyl succinate

28-(benzyloxy)-28-oxoolean-12-en-3-yl 4-{[5-oxido-4-(phenylsulfonyl)-1,2,5-oxadiazol-3-yl]oxy}butyl succinate

28-(benzyloxy)-28-oxoolean-12-en-3-yl 4-{[5-oxido-4-(phenylsulfonyl)-1,2,5-oxadiazol-3-yl]oxy}benzyl succinate

28-(benzyloxy)-28-oxoolean-12-en-3-yl 3-{[5-oxido-4-(phenylsulfonyl)-1,2,5-oxadiazol-3-yl]oxy}benzyl succinate