4,5-dichloro-2-phenylpyridazin-3(2H)-one

Base Information

Chemical Name:4,5-dichloro-2-phenylpyridazin-3(2H)-one
CAS No.:1698-53-9
Molecular Formula:C10H6 Cl2 N2 O
Molecular Weight:241.076
Hs Code.:29339980
European Community (EC) Number:216-917-6
NSC Number:642642,224369
UNII:N78AH78WRV
DSSTox Substance ID:DTXSID60168751
Nikkaji Number:J1.774D
Wikidata:Q83038373
ChEMBL ID:CHEMBL610198
Mol file:1698-53-9.mol

Synonyms:2-phenyl-4,5-dichloro-3-pyridazinone

Suppliers and Price of 4,5-dichloro-2-phenylpyridazin-3(2H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Phenyl-4,5-dichloro-6-pyridazone
10g
$ 1260.00

TRC
1-Phenyl-4,5-dichloro-6-pyridazone
1g
$ 160.00

TCI Chemical
4,5-Dichloro-2-phenyl-3(2H)-pyridazinone >98.0%(GC)
1g
$ 22.00

TCI Chemical
4,5-Dichloro-2-phenyl-3(2H)-pyridazinone >98.0%(GC)
5g
$ 61.00

Sigma-Aldrich
1-Phenyl-4,5-dichloro-6-pyridazone ≥99%
5g
$ 65.00

Medical Isotopes, Inc.
1-Phenyl-4,5-dichloro-6-pyridazone
1 g
$ 650.00

Crysdot
4,5-Dichloro-2-phenylpyridazin-3(2H)-one 97%
25g
$ 321.00

Crysdot
4,5-Dichloro-2-phenylpyridazin-3(2H)-one 97%
10g
$ 149.00

Crysdot
4,5-Dichloro-2-phenylpyridazin-3(2H)-one 97%
5g
$ 80.00

Chem-Impex
4,5-Dichloro-2-phenyl-3(2H)-pyridazinone,≥98%(GC) ≥98%(GC)
1G
$ 25.70

Total 66 raw suppliers

Chemical Property of 4,5-dichloro-2-phenylpyridazin-3(2H)-one

Chemical Property:

Appearance/Colour:light beige crystalline powder
Vapor Pressure:4.74E-05mmHg at 25°C
Melting Point:164-166 °C(lit.)
Refractive Index:1.661
Boiling Point:354.7°Cat760mmHg
PKA:-3.44±0.60(Predicted)
Flash Point:168.3°C
PSA：34.89000
Density:1.55g/cm³
LogP:2.53930
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:239.9857182
Heavy Atom Count:15
Complexity:332

Purity/Quality:

98% ^*data from raw suppliers

1-Phenyl-4,5-dichloro-6-pyridazone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C(=O)C(=C(C=N2)Cl)Cl
Uses 1-Phenyl-4,5-dichloro-6-pyridazone is part of a group of arylated pyridazin-3(2H)-one compounds that act as anti-cancer agents. 1-Phenyl-4,5-dichloro-6-pyridazone also has herbicidal activity.

Technology Process of 4,5-dichloro-2-phenylpyridazin-3(2H)-one

There total 9 articles about 4,5-dichloro-2-phenylpyridazin-3(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 766-40-5
Mucochloric acid

: 100-63-0
phenylhydrazine

: 1698-53-9
4,5-dichloro-1-phenylpyridazin-6-one

Guidance literature:: With hydrogenchloride; water; for 3h; Reflux;
DOI:10.1016/j.bmc.2009.08.067

Reference yield: 93.2%

: 1698-53-9
4,5-dichloro-1-phenylpyridazin-6-one

Guidance literature:: With sodium carbonate; In water; at 0 - 20 ℃;

With acetic acid; for 0.5h; Reflux;

Reference yield: 85.0%

: 1698-60-8,58858-18-7
chloridazon

: 1698-53-9
4,5-dichloro-1-phenylpyridazin-6-one

Guidance literature:: With pyrylium tetrafluoroborate; magnesium chloride; In acetonitrile; for 16h; Reagent/catalyst; Solvent; Heating; Sealed tube;
DOI:10.1038/s41557-021-00812-0