7,7,8,8-Tetramethyl-3-methylene-5-phenoxy-1,4,6,9-tetraoxa-5λ⁵-phospha-spiro[4.4]nonan-2-one

Base Information

• Chemical Name: 7,7,8,8-Tetramethyl-3-methylene-5-phenoxy-1,4,6,9-tetraoxa-5λ⁵-phospha-spiro[4.4]nonan-2-one
• CAS No.: 105930-58-3
• Molecular Formula: C₁₅H₁₉O₆P
• Molecular Weight: 326.286
• Mol file: 105930-58-3.mol

Synonyms:7,7,8,8-Tetramethyl-3-methylene-5-phenoxy-1,4,6,9-tetraoxa-5λ⁵-phospha-spiro[4.4]nonan-2-one

Chemical Property of 7,7,8,8-Tetramethyl-3-methylene-5-phenoxy-1,4,6,9-tetraoxa-5λ⁵-phospha-spiro[4.4]nonan-2-one

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7,7,8,8-Tetramethyl-3-methylene-5-phenoxy-1,4,6,9-tetraoxa-5λ⁵-phospha-spiro[4.4]nonan-2-one

There total 1 articles about 7,7,8,8-Tetramethyl-3-methylene-5-phenoxy-1,4,6,9-tetraoxa-5λ⁵-phospha-spiro[4.4]nonan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bromopyruvic acid (1113-59-3) + phenoxy-2 tetramethyl-4,4,5,5 dioxaphospholane-1,3,2 (14812-61-4) → 7,7,8,8-Tetramethyl-3-methylene-5-phenoxy-1,4,6,9-tetraoxa-5λ5-phospha-spiro[4.4]nonan-2-one (105930-58-3)

Guidance literature:

With triethylamine; In acetone; at 20 ℃; for 1h;

DOI:10.1021/jo00377a030

Reference yield: 100.0%

7,7,8,8-Tetramethyl-3-methylene-5-phenoxy-1,4,6,9-tetraoxa-5λ5-phospha-spiro[4.4]nonan-2-one (105930-58-3) → 2-hydroxy-4,4,5,5-tetramethyl<1,3,2>dioxaphospholane-2-oxide (13882-05-8) + 2-oxo-propionic acid (127-17-3) + phenol (108-95-2,27073-41-2)

Guidance literature:

With water; In acetone; at 20 ℃; for 24h;

DOI:10.1021/jo00377a030

Reference yield: 46.0%

ethylene glycol (107-21-1) + 7,7,8,8-Tetramethyl-3-methylene-5-phenoxy-1,4,6,9-tetraoxa-5λ5-phospha-spiro[4.4]nonan-2-one (105930-58-3) → 2-(4,4,5,5-Tetramethyl-2-oxo-2λ5-[1,3,2]dioxaphospholan-2-yloxy)-ethanol (105900-05-8) + 2-oxo-propionic acid (127-17-3)

Guidance literature:

In chloroform-d1; at 20 ℃; for 48h;

DOI:10.1021/jo00377a030

upstream raw materials:

bromopyruvic acid

phenoxy-2 tetramethyl-4,4,5,5 dioxaphospholane-1,3,2

Downstream raw materials:

trimethyl phosphite

2-methoxy-4,4,5,5-tetramethyl-[1,3,2]dioxaphospholane 2-oxide

2,2,3,3,7,7,8,8-octamethyl-1,4,6,9-tetraoxa-5λ⁵-phospha-spiro[4.4]nonane

2-(4,4,5,5-Tetramethyl-2-oxo-2λ⁵-[1,3,2]dioxaphospholan-2-yloxy)-ethanol