(2-Propionyl-phenyl)-propargylether

Base Information

• Chemical Name: (2-Propionyl-phenyl)-propargylether
• CAS No.: 60505-20-6
• Molecular Formula: C₁₂H₁₂O₂
• Molecular Weight: 188.226
• Mol file: 60505-20-6.mol

Synonyms:(2-Propionyl-phenyl)-propargylether

Chemical Property of (2-Propionyl-phenyl)-propargylether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-Propionyl-phenyl)-propargylether

There total 1 articles about (2-Propionyl-phenyl)-propargylether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2-Hydroxy-phenyl)-propan-1-on (610-99-1) + propargyl bromide (106-96-7) → (2-Propionyl-phenyl)-propargylether (60505-20-6)

Guidance literature:

With potassium carbonate;

DOI:10.1002/hlca.19760590233

Reference yield: 50.0%

cyclohex-1-en-1-yl trifluoromethane sulfonate (28075-50-5) + (2-Propionyl-phenyl)-propargylether (60505-20-6) → 1-(2-(3-cyclohexenylprop-2-ynyloxy)phenyl)propan-1-one (1040475-07-7)

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; diethylamine; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

DOI:10.1021/ol801265s

Reference yield: 32.0%

(2-Propionyl-phenyl)-propargylether (60505-20-6) + edaravone (89-25-8) → (11bS)-11b-ethyl-3,11b-dihydro-1-methyl-3-phenyl-6H-chromeno[4',3':4,5]pyrano[2,3-c]pyrazole (1437324-59-8)

Guidance literature:

With triethylammonium acetate; zinc(II) oxide; at 150 ℃; for 7h;

DOI:10.1007/s00706-012-0873-7

upstream raw materials:

1-(2-Hydroxy-phenyl)-propan-1-on

propargyl bromide

Downstream raw materials:

1-(2-(3-cyclohexenylprop-2-ynyloxy)phenyl)propan-1-one

(11bS)-11b-ethyl-3,11b-dihydro-1-methyl-3-phenyl-6H-chromeno[4',3':4,5]pyrano[2,3-c]pyrazole